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ω-芋螺毒素MVIIC

ω-芋螺毒素MVIIC用途

ω-Conotoxin MVIIC 是一种 N 和 P/Q 型钙通道 (Ca2+ channel) 阻滞剂,可显着阻断 11-keto-βboswellic acid 介导的谷氨酸释放抑制。

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ω-芋螺毒素MVIIC名称

[ CAS 号 ]:
147794-23-8

[ 中文名 ]:
OMEGA-芋螺毒素 M VIIC

[ 英文名 ]:
ω-Conotoxin MVIIC

[英文别名 ]:

CTX MVIIC
conotoxin MVIIC
omega-Conotoxin M VIIC
Snx 230
conotoxin MVIIC_smartox

ω-芋螺毒素MVIIC生物活性

[ 描述 ]:

ω-Conotoxin MVIIC 是一种 N 和 P/Q 型钙通道 (Ca2+ channel) 阻滞剂,可显着阻断 11-keto-βboswellic acid 介导的谷氨酸释放抑制。

[ 相关类别 ]:

信号通路 >> 跨膜转运 >> 钙通道

研究领域 >> 神经疾病

[参考文献]

[1]. Cheng Wei Lu, et al. 11-Keto-β-Boswellic Acid Attenuates Glutamate Release and Kainic Acid-Induced Excitotoxicity in the Rat Hippocampus. Planta Med. 2020 Apr;86(6):434-441.

ω-芋螺毒素MVIIC物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 分子式 ]:
C₁₀₆H₁₇₈N₄₀O₃₂S₇

[ 分子量 ]:
2749.251

[ 精确质量 ]:
2747.157471

[ PSA ]:
1372.92000

[ LogP ]:
-20.33

[ 外观性状 ]:
白色冻干的固体

[ 折射率 ]:
1.723

[ 储存条件 ]:
-20°C，避光干燥

ω-芋螺毒素MVIIC安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
UN 3172

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

ω-芋螺毒素MVIIC文献

Mechanisms underlying mechanosensitivity of mesenteric afferent fibers to vascular flow.

Am. J. Physiol. Gastrointest. Liver Physiol. 293(2) , G422-8, (2007)

Spinal afferent neurons, with endings in the intestinal mesenteries, have been shown to respond to changes in vascular perfusion rates. The mechanisms underlying this sensitivity were investigated in ...

Glutamate regulates neurite outgrowth of cultured descending brain neurons from larval lamprey.

Dev. Neurobiol. 67(2) , 173-88, (2007)

In larval lamprey, descending brain neurons, which regenerate their axons following spinal cord injury, were isolated and examined in cell culture to identify some of the factors that regulate neurite...

Effects of Ca2+ channel antagonists on acetylcholine and catecholamine releases in the in vivo rat adrenal medulla.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 287(1) , R161-6, (2004)

To elucidate the types of voltage-dependent Ca(2+) channels controlling ACh and catecholamine releases in the in vivo adrenal medulla, we implanted microdialysis probes in the left adrenal medulla of ...

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