L-抗坏血酸棕榈酸酯
L-抗坏血酸棕榈酸酯结构式
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常用名 | L-抗坏血酸棕榈酸酯 | 英文名 | L-Ascorbyl 6-palmitate |
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| CAS号 | 137-66-6 | 分子量 | 414.533 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 512.7±50.0 °C at 760 mmHg | |
| 分子式 | C22H38O7 | 熔点 | 115-118 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 164.4±23.6 °C |
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Apolar Radical Initiated Conjugated Autoxidizable Triene (ApoCAT) Assay: Effects of Oxidant Locations on Antioxidant Capacities and Interactions.
J. Agric. Food Chem. 63 , 7546-55, (2015) Development of an antioxidant assay explaining antioxidant behaviors in complex food systems has been a challenging topic for food scientists. This research aimed to investigate antioxidant capacities and interactions of selected synthetic antioxidants and co... |
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Molecular encapsulation of ascorbyl palmitate in preformed V-type starch and amylose.
Carbohydr. Polym. 111 , 256-63, (2014) In the present study, we introduce a simple method to prepare inclusion complexes by "inserting" guest molecules into preformed "empty" V-type amylose helices. Ascorbyl palmitate (AscP) was used as a model guest material to investigate the effect of solvent e... |
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Influence of fatty acid on lipase-catalyzed synthesis of ascorbyl esters and their free radical scavenging capacity.
Biotechnol. Appl. Biochem. 62 , 458-66, (2015) Fatty acid (FA) ascorbyl esters are recently emerging food, cosmetic, and pharmaceutical additives, which can be prepared in an eco-friendly way by using lipases as catalysts. Because they are amphiphilic molecules, which possess high free radical scavenging ... |
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Engineering of nano-crystalline drug suspensions: employing a physico-chemistry based stabilizer selection methodology or approach.
Int. J. Pharm. 476(1-2) , 277-88, (2015) This paper describes a systematic approach to select optimum stabilizer for the preparation of nano-crystalline suspensions of an active pharmaceutical ingredient (API). The stabilizer can be either a dispersant or a combination of dispersant and wetting agen... |
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Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase.
Eur. J. Med. Chem. 46 , 4419-29, (2011) Bacterial hyaluronan lyases (Hyal) degrade hyaluronan, an important component of the extracellular matrix, and are involved in microbial spread. Hyal inhibitors may serve as tools to study the role of the enzyme, its substrates and products in the course of b... |
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Novel 6-O-acylated vitamin C derivatives as hyaluronidase inhibitors with selectivity for bacterial lyases.
Bioorg. Med. Chem. Lett. 16 , 5313-6, (2006) Previously, we identified ascorbic acid 6-O-hexadecanoate as an up to 1500 times more potent inhibitor of bacterial and bovine hyaluronidases than the parent compound, vitamin C, and determined a crystal structure of hyaluronidase from Streptococcus pneumonia... |
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Sterol superlattice affects antioxidant potency and can be used to assess adverse effects of antioxidants.
Anal. Biochem. 382(1) , 1-8, (2008) We have developed a fluorescence method to examine how membrane sterol lateral organization affects the potency of antioxidants, and used this information to evaluate possible adverse effects of lipid-soluble antioxidants seen in recent clinical studies. In t... |
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The lipophilic vitamin C derivative, 6-o-palmitoylascorbate, protects human lymphocytes, preferentially over ascorbate, against X-ray-induced DNA damage, lipid peroxidation, and protein carbonylation.
Mol. Cell Biochem. 394(1-2) , 247-59, (2014) The aim of this study was to investigate protective effects of the lipophilic vitamin C derivative, 6-o-palmitoylascorbate (PlmtVC), against X-ray radiation-induced damages including cell death, DNA double-strand breaks (DSBs), lipid peroxidation, and protein... |
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Pursuit of oxidation behavior for conjugated polyenoyl glycerols and establishment of their novel oxidation prevention method.
J. Oleo Sci. 58(6) , 295-301, (2009) Although conjugated oils are paid much attentions to their interesting physiological properties such as anticancer, anti-arteriosclerosis, anti-hypertension activities, loss in body fat etc, there is few information on their oxidation behavior. In the present... |
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A new approach for increasing ascorbyl palmitate stability by addition of non-irritant co-antioxidant.
AAPS PharmSciTech 11(3) , 1485-92, (2010) The aim of this work was to test innovative approach for enhancing ascorbyl palmitate stability in microemulsions for topical application by addition of newly synthesized co-antioxidant 4-(tridecyloxy)benzaldehyde oxime (TDBO) and to investigate its antioxida... |