红霉素
红霉素结构式
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常用名 | 红霉素 | 英文名 | Erythromycin |
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| CAS号 | 114-07-8 | 分子量 | 733.927 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 818.4±65.0 °C at 760 mmHg | |
| 分子式 | C37H67NO13 | 熔点 | 138-140ºC | |
| MSDS | 中文版 美版 | 闪点 | 448.8±34.3 °C |
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Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance.
Biol. Pharm. Bull. 37(8) , 1383-9, (2014) In the present study, we examined the interaction of antimicrobial agents with four model lipid membranes that mimicked mammalian cell membranes and Gram-positive and -negative bacterial membranes and analyzed the binding kinetics using our surface plasmon re... |
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Live-cell and super-resolution imaging reveal that the distribution of wall-associated protein A is correlated with the cell chain integrity of Streptococcus mutans.
Mol. Oral Microbiol. 30 , 376-83, (2015) Streptococcus mutans is a primary pathogen responsible for dental caries. It has an outstanding ability to form biofilm, which is vital for virulence. Previous studies have shown that knockout of Wall-associated protein A (WapA) affects cell chain and biofilm... |
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Mechanisms involved in quinolone resistance in Mycoplasma mycoides subsp. capri.
Vet. J. 204 , 327-32, (2015) Mycoplasma mycoides subsp. capri is a causative agent of contagious agalactia in goats. In this study, M. mycoides subsp. capri mutants were selected for resistance to fluoroquinolones (norfloxacin, enrofloxacin and ciprofloxacin) by serial passes in broth wi... |
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Screening of a Leptospira biflexa mutant library to identify genes involved in ethidium bromide tolerance.
Appl. Environ. Microbiol. 80(19) , 6091-103, (2014) Leptospira spp. are spirochete bacteria comprising both pathogenic and free-living species. The saprophyte L. biflexa is a model bacterium for studying leptospiral biology due to relative ease of culturing and genetic manipulation. In this study, we construct... |
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Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens.
J. Vet. Pharmacol. Ther. 37(4) , 406-12, (2014) Butyrate, a commonly applied feed additive in poultry nutrition, can modify the expression of certain genes, including those encoding cytochrome P450 (CYP) enzymes. In comparative in vitro and in vivo experiments, the effect of butyrate on hepatic CYP genes w... |
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Cell wall-anchored nuclease of Streptococcus sanguinis contributes to escape from neutrophil extracellular trap-mediated bacteriocidal activity.
PLoS ONE 9(8) , e103125, (2014) Streptococcus sanguinis, a member of the commensal mitis group of streptococci, is a primary colonizer of the tooth surface, and has been implicated in infectious complications including bacteremia and infective endocarditis. During disease progression, S. sa... |
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Genotypes and oxacillin resistance of Staphylococcus aureus from chicken and chicken meat in Poland.
Poult. Sci. 93(12) , 3179-86, (2014) The genotypes and oxacillin resistance of 263 Staphylococcus aureus isolates cultured from chicken cloacae (n = 138) and chicken meat (n = 125) was analyzed. Fifteen spa types were determined in the studied S. aureus population. Among 5 staphylococcal protein... |
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Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum.
BMC Biol. 13 , 52, (2015) Malaria invasion of red blood cells involves multiple parasite-specific targets that are easily accessible to inhibitory compounds, making it an attractive target for antimalarial development. However, no current antimalarial agents act against host cell inva... |
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Population Structure and Oxacillin Resistance of Staphylococcus aureus from Pigs and Pork Meat in South-West of Poland.
Biomed Res. Int. 2015 , 141475, (2015) The genotypes and oxacillin resistance of 420 S. aureus isolates from pigs (n = 203) and pork (n = 217) were analyzed. Among 18 spa types detected in S. aureus from pig t011, t021, t034, t091, t318, t337, and t1334 were the most frequent. Among 30 spa types f... |
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Role of the AheABC efflux pump in Aeromonas hydrophila intrinsic multidrug resistance.
Antimicrob. Agents Chemother. 52 , 1559-63, (2008) Gene inactivation and complementation experiments showed that the tripartite AheABC efflux pump of Aeromonas hydrophila extruded at least 13 substrates, including nine antibiotics. The use of phenylalanine-arginine-beta-naphthylamide (PAbetaN) revealed an add... |