克林霉素盐酸盐 一水合物
克林霉素盐酸盐 一水合物结构式
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常用名 | 克林霉素盐酸盐 一水合物 | 英文名 | clindamycin hydrochloride |
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| CAS号 | 58207-19-5 | 分子量 | 479.459 | |
| 密度 | N/A | 沸点 | 647ºC at 760 mmHg | |
| 分子式 | C18H36Cl2N2O6S | 熔点 | 143ºC | |
| MSDS | 中文版 美版 | 闪点 | 345.1ºC |
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Performance characterization of a quantitative liquid chromatography-tandem mass spectrometric method for 12 macrolide and lincosamide antibiotics in salmon, shrimp and tilapia.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 203-10, (2014) This paper describes an extension and performance characterization of a quantitative confirmatory multi-residue liquid chromatography-tandem mass spectrometric method for residues of macrolide and lincosamide antibiotics, originally validated for application ... |
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Development of a method to quantify clindamycin in vitreous humor of rabbits' eyes by UPLC-MS/MS: application to a comparative pharmacokinetic study and in vivo ocular biocompatibility evaluation.
J. Pharm. Biomed. Anal. 102 , 346-52, (2015) Ocular toxoplasmosis may result in uveitis in the posterior segment of the eye, leading to severe visual complications. Clindamycin-loaded poly(lactide-co-glycolide) (PLGA) implants could be applied to treat the ocular toxoplasmosis. In this study, the pharma... |
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A biodegradable antibiotic-impregnated scaffold to prevent osteomyelitis in a contaminated in vivo bone defect model.
Eur. Cell. Mater. 27 , 332-49, (2014) Open fractures are at risk of serious infection and, if infected, require several surgical interventions and courses of systemic antibiotics. We investigated a new injectable formulation that simultaneously hardens in vivo to form a porous scaffold for bone r... |
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Rare variations in IL36RN in severe adverse drug reactions manifesting as acute generalized exanthematous pustulosis.
J. Invest. Dermatol. 133(7) , 1904-7, (2013)
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Enantioseparation of basic chiral compounds on a clindamycin phosphate-silica/zirconia hybrid monolith by capillary electrochromatography.
J. Chromatogr. A. 1356 , 289-93, (2014) An organic-inorganic silica/zirconia hybrid monolithic capillary column was prepared by sol-gel process in a fused-silica capillary by using triethoxysilylpropylcarbamate (TEOSPC) derivative of clindamycin phosphate (CLIP) as a chiral selector. A sol solution... |
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Effects of antibiotic physicochemical properties on their release kinetics from biodegradable polymer microparticles.
Pharm. Res. 31(12) , 3379-89, (2014) This study investigated the effects of the physicochemical properties of antibiotics on the morphology, loading efficiency, size, release kinetics, and antibiotic efficacy of loaded poly(DL-lactic-co-glycolic acid) (PLGA) microparticles (MPs) at different loa... |
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Antibiotic prophylaxis for ED patients with simple hand lacerations: a feasibility randomized controlled trial.
Am. J. Emerg. Med. 32(7) , 768-71, (2014) The benefit of antibiotic prophylaxis for simple hand lacerations (lacerations that do not involve special structures) has not been adequately studied.To assess the feasibility of a randomized controlled trial to determine the role of antibiotic prophylaxis i... |
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Molecular characterization and antibiotic resistance of clinical isolates of methicillin-resistant Staphylococcus aureus obtained from Southeast of Iran (Kerman).
APMIS 122(5) , 405-11, (2014) Staphylococcus aureus infections, particularly infections caused by methicillin-resistant S. aureus (MRSA) strains, are emerging as a major public health problem. The aim of this study was to determine the prevalence of MRSA, antibiotic resistance profile and... |
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Efficacy of clindamycin hydrochloride capsules for the treatment of deep pyoderma due to Staphylococcus intermedius infection in dogs.
Can. Vet. J. 39(12) , 753-6, (1998) Clindamycin hydrochloride capsules (11 mg/kg body weight, q24 h) were administered orally to 20 dogs with deep staphylococcal pyoderma. Response to therapy was excellent in 100% of the dogs. Duration of therapy varied from 21 to 91 d, with an average duration... |
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D-Zone test for detection of inducible clindamycin resistance using SirScan paper disks and Rosco Neo-Sensitabs at 25 and 15 mm distances.
J. Med. Microbiol. 63(Pt 8) , 1052-4, (2014) Clindamycin is a possible antibiotic treatment of infections by Gram-positive cocci. However, its use can be limited by inducible clindamycin resistance. To screen for the presence of this type of resistance, the D-zone test is used. The aim of this study was... |