β-内啡肽
β-内啡肽结构式
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常用名 | β-内啡肽 | 英文名 | β-Endorphin (human) trifluoroacetate salt |
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| CAS号 | 61214-51-5 | 分子量 | 3464.98000 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C158H251N39O46S | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Evidence for the existence of the beta-endorphin-sensitive "epsilon-opioid receptor" in the brain: the mechanisms of epsilon-mediated antinociception.
Jpn. J. Pharmacol. 76 , 233-253, (1998) Recently, mu-, delta- and kappa-opioid receptors have been cloned and relatively well-characterized. In addition to three major opioid receptor types, more extensive studies have suggested the possible existence of other opioid receptor types that can be clas... |
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Beta-endorphin and the immune system--possible role in autoimmune diseases.
Autoimmunity 21 , 161-171, (1995) The immune system and the neuroendocrine system are closely interconnected having such means of bidirectional communication and regulation. In this review, a hypothesis is put forward regarding the possible role of beta-endorphins in the pathogenesis of autoi... |
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The antinociception induced by beta-endorphin administered intrathecally is mediated by the activation of mu- and kappa-opioid receptors in the rat.
Naunyn Schmiedebergs Arch. Pharmacol. 351 , 464-468, (1995) The antinociception induced by beta-endorphin given supraspinally has been previously demonstrated to be mediated by the stimulation of epsilon-, but not mu-, delta- or kappa-opioid receptors in rats and mice. The present study was designed to determine what ... |
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Hypothalamo-pituitary portal blood concentrations of beta-endorphin during suckling in the ewe.
J. Reprod. Fertil. 79(2) , 397-408, (1987) Matched hypothalamo-pituitary portal and jugular blood samples were collected over about 6 h from 7 lactating Corriedale ewes penned with their lambs, and a careful record was kept of ewe/lamb behaviour. Hypothalamo-pituitary portal blood concentrations of be... |
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Proopiomelanocortin signaling system is operating in mast cells.
J. Invest. Dermatol. 126(9) , 1934-6, (2006) The proopiomelanocortin (POMC) system is the central coordinator of the systemic endocrine responses to sustained stress. It has been recently discovered that mast cells also display regulated production of POMC peptides. Since at the tissue level mast cells ... |
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Regulation of human epidermal melanocyte biology by beta-endorphin.
J. Invest. Dermatol. 120(6) , 1073-80, (2003) beta-Endorphin is an opioid peptide cleaved from the precursor pro-hormone pro-opiomelanocortin, from which other peptides such as adrenocorticotropic hormone, beta-lipotropic hormone, and alpha-melanocyte-stimulating hormone are also derived. alpha-Melanocyt... |
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Beta-endorphin- and GABA-mediated depressor effect of specific electroacupuncture surpasses pressor response of emotional circuit.
Peptides 22(9) , 1465-70, (2001) It has been proved that input of specific electroacupuncture (EA) can activate beta-endorphin(beta-EP)ergic and noradrenergic neurons projecting to the rostral ventrolateral medulla (RVL), the latter acting upon the RVL-GABAergic interneurons, thereby produce... |
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beta-endorphin stimulates cytokeratin 16 expression and downregulates mu-opiate receptor expression in human epidermis.
J. Invest. Dermatol. 114(3) , 527-32, (2000) It has been reported that opioid peptides modulate the differentiation of normal human keratinocytes and that mu-opiate receptors are expressed in human epidermis. The regulation of keratinocyte differentiation is particularly important in psoriasis, and one ... |