蔗糖十二烷酸酯

蔗糖十二烷酸酯结构式
蔗糖十二烷酸酯结构式
品牌特惠专场
常用名 蔗糖十二烷酸酯 英文名 sucrose monolaurate
CAS号 25339-99-5 分子量 524.59900
密度 1.338g/cm3 沸点 720.293ºC at 760 mmHg
分子式 C24H44O12 熔点 150-152ºC
MSDS 中文版 美版 闪点 234.787ºC

Disruption of sphingolipid metabolism augments ceramide-induced autophagy in preeclampsia.

Autophagy 11 , 653-69, (2015)

Bioactive sphingolipids including ceramides are involved in a variety of pathophysiological processes by regulating cell death and survival. The objective of the current study was to examine ceramide metabolism in preeclampsia, a serious disorder of pregnancy...

Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain.

J. Biol. Chem. 290 , 13622-39, (2015)

Regulators of G protein signaling control the duration and extent of signaling via G protein-coupled receptor (GPCR) pathways by accelerating the GTP hydrolysis on G protein α subunits thereby promoting termination of GPCR signaling. A member of this family, ...

Disintegration of protein microbubbles in presence of acid and surfactants: a multi-step process.

Soft Matter 11 , 6403-11, (2015)

The stability of protein microbubbles against addition of acid or surfactants was investigated. When these compounds were added, the microbubbles first released the encapsulated air. Subsequently, the protein shell completely disintegrated into nanometer-size...

Natural microemulsions: formulation design and skin interaction.

Eur. J. Pharm. Biopharm. 81(3) , 557-62, (2012)

Microemulsions are thermodynamically stable, colloidal drug delivery systems. This study presents the first substantiated comparison of natural, skin-compatible and biodegradable surfactants in terms of their suitability to form isotropic microemulsions and t...

Inhibitory effects of sucrose fatty acid esters on survival of Yersinia enterocolitica on eggshell surface and use of blue lake as indicator of bacterial penetration into eggs.

J. Appl. Microbiol. 106(3) , 774-83, (2009)

To determine the effectiveness of sucrose monolaurate (SML) and sucrose monocaprate (SMC), alone and in combination with ethylenediaminetetraacetic acid (EDTA), propionic acid (PA) or citric acid (CA) in reducing mesophilic aerobic bacteria (MAB) and Yersinia...

Sucrose monolaurate synthesis with Protex 6L immobilized on electrospun TiO2 nanofiber.

Biotechnol. Lett. 33(9) , 1831-5, (2011)

TiO(2) nanofibers with uniform diameter about 125 nm were prepared based on sol-gel process and electrospinning technology. Protex 6L, an industrial alkaline protease, was covalently immobilized on TiO(2) nanofiber through γ-aminopropyltriethoxysilane modific...

Sucrose monolaurate improves the efficacy of sodium hypochlorite against Escherichia coli O157:H7 on spinach.

Int. J. Food Microbiol. 145(1) , 64-8, (2011)

It is well-recognized that chlorine has limited efficacy when applied to inactivate pathogens on fresh produce. One of the many factors limiting efficacy is the high interfacial tension of chlorine-based sanitizers that limits the access of chlorine to the mi...

Phospholipids-embedded fully dilutable liquid nanostructures. Part 2: The role of sodium diclofenac.

Colloids Surf. B Biointerfaces 81(2) , 422-9, (2010)

Complex pseudo-ternary phase diagrams based on sucrose monolaurate (SE), propylene glycol (PG), and phosphatidylcholine (PC) as the "surfactant phase"; triacetin (TA) and decaglycerol ester (10G1CC) as the "oil phase"; and water as the aqueous phase were cons...

Investigating the stability of the nonionic surfactants tocopheryl polyethylene glycol succinate and sucrose laurate by HPLC-MS, DAD, and CAD.

J. Pharm. Sci. 100(5) , 1773-82, (2011)

High-performance liquid chromatography (HPLC) methods using a charged aerosol detector (CAD), a mass selective detector (MSD), and a diode array detector (DAD) were developed to characterize the nonionic surfactants d-α-tocopheryl polyethylene glycol (1000) s...

In vitro-in vivo study of CoQ10-loaded lipid nanoparticles in comparison with nanocrystals.

Int. J. Pharm. 419(1-2) , 255-9, (2011)

The present work described the effect of CoQ10 dissolution characteristics in nanocrystals and lipid nanoparticles (LNs) on its oral absorption in rats. Nanocrystals and LNs were prepared by melt-high pressure homogenization and sucrose monolaurate was used a...