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3-苯基丁酸

3-苯基丁酸结构式
3-苯基丁酸结构式
品牌特惠专场
常用名 3-苯基丁酸 英文名 3-Phenylbutyric acid
CAS号 4593-90-2 分子量 164.201
密度 1.1±0.1 g/cm3 沸点 288.0±0.0 °C at 760 mmHg
分子式 C10H12O2 熔点 35-38 °C(lit.)
MSDS 中文版 美版 闪点 170.2±13.9 °C

Adsorption of small hydroxy acids on glass: a pitfall in quantitative urinary organic acid analysis by GC-MS.

J. Inherit. Metab. Dis. 22(3) , 293-6, (1999)

Induction of histone acetylation and growth regulation in eryrthroleukemia cells by 4-phenylbutyrate and structural analogs.

Anticancer Res. 19(3A) , 1971-6, (1999)

The objective of this investigation was to study the relationship between histone acetylation and growth inhibition by 4-phenylbutyrate and structural analogs. Inhibition of growth of DS19 mouse erythroleukemia cells and K562 human leukemic cells by 4-phenylb...

Enantioselective Metabolism of Chiral 3-Phenylbutyric Acid, an Intermediate of Linear Alkylbenzene Degradation, by Rhodococcus rhodochrous PB1.

Appl. Environ. Microbiol. 62(3) , 749-55, (1996)

Rhodococcus rhodochrous PB1 was isolated from compost soil by selective culture with racemic 3-phenylbutyric acid as the sole carbon and energy source. Growth experiments with the single pure enantiomers as well as with the racemate showed that only one of th...

Oxidation of aliphatic, branched chain, and aromatic hydrocarbons by Nocardia cyriacigeorgica isolated from oil-polluted sand samples collected in the Saudi Arabian Desert.

J. Basic Microbiol. 50(3) , 241-53, (2010)

A soil bacterium isolated from oil-polluted sand samples collected in the Saudi Arabian Desert has been determined as Nocardia cyriacigeorgica, which has a high capacity of degrading and utilizing a broad range of hydrocarbons. The metabolic pathways of three...

Configurational analysis of chiral acids as O-trifluoroacetylated (-)-menthyl esters by achiral dual-capillary column gas chromatography.

J. Chromatogr. A. 891(2) , 257-66, (2000)

The simultaneous enantiomeric separation of 30 racemic acids including 24 hydroxy acids in a single analysis is described for the determination of their absolute configurations. It involves the conversion of each enantiomer into diastereomeric O-trifluoroacet...

Epigenetic regulation of microRNA expression in colorectal cancer.

Int. J. Cancer 125(11) , 2737-43, (2009)

In the last years, microRNAs (miRNA) have emerged as new molecular players involved in carcinogenesis. Deregulation of miRNAs expression has been shown in different human cancer but the molecular mechanism underlying the alteration of miRNA expression is unkn...

Thermodynamics of hydrogen bond and hydrophobic interactions in cyclodextrin complexes.

Biophys. J. 71(4) , 2144-54, (1996)

Values of K, delta G(o), delta H(o), delta S(o) and delta C(po) for the binding reaction of small organic ligands forming 1:1 complexes with either alpha- or beta-cyclodextrin were obtained by titration calorimetry from 15 degrees C to 45 degrees C. A hydroge...

Natural diversity to guide focused directed evolution.

ChemBioChem. 11(13) , 1861-6, (2010)

Simultaneous multiple site-saturation mutagenesis was performed at four active-site positions of an esterase from Pseudomonas fluorescens to improve its ability to convert 3-phenylbutyric acid esters (3-PBA) in an enantioselective manner. Based on an appropri...

Xenobiotic triacylglycerol formation in isolated hepatocytes.

Biochem. Pharmacol. 41(8) , 1179-85, (1991)

The formation of neutral lipophilic metabolites from five xenobiotic carboxylic acids was studied in isolated rat hepatocytes. Oleic acid was used as a positive control. Rates of formation of lipids lay in the order: oleic acid greater than phytanic acid grea...

A combination of in vivo selection and cell sorting for the identification of enantioselective biocatalysts.

Angew. Chem. Int. Ed. Engl. 50(37) , 8584-7, (2011)