蛋白激酶A 来源于牛心脏
蛋白激酶A 来源于牛心脏结构式
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常用名 | 蛋白激酶A 来源于牛心脏 | 英文名 | Protein serine/threonine kinase |
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| CAS号 | 9026-43-1 | 分子量 | 119.11916 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C4H9NO3 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Expression and localization of five members of the testis-specific serine kinase (Tssk) family in mouse and human sperm and testis.
Mol. Hum. Reprod. 17(1) , 42-56, (2011) Members of the testis-specific serine/threonine kinases (Tssk) family may have a role in sperm differentiation in the testis and/or fertilization. To gain insight into the functional relevance of these kinases, their expression was examined both at the mRNA a... |
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Hipk is an essential protein that promotes Notch signal transduction in theDrosophilaeye by inhibition of the global co-repressor Groucho
Dev. Biol. 325(1) , 263-72, (2009) Homeodomain interacting protein kinase (Hipk) is a member of a novel family of serine/threonine kinases. Extensive biochemical studies of vertebrate homologs, particularly Hipk2, have identified a growing list of interactors, including proteins involved in tr... |
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Drosophila Smt3 negatively regulates JNK signaling through sequestering Hipk in the nucleus.
Development 138(12) , 2477-85, (2011) Post-translational modification by the small ubiquitin-related modifier (SUMO) is important for a variety of cellular and developmental processes. However, the precise mechanism(s) that connects sumoylation to specific developmental signaling pathways remains... |
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CIPK9: a calcium sensor-interacting protein kinase required for low-potassium tolerance in Arabidopsis.
Cell Res. 17(5) , 411-21, (2007) Potassium is one of the major macro-nutrients essential for a number of cellular processes in plants. Low potassium level in the soil represents a limiting factor for crop production. Recent studies have identified potassium transporters that are involved in ... |
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Tubulin binds to the cytoplasmic loop of TRESK background K⁺ channel in vitro.
PLoS ONE 9(5) , e97854, (2014) The cytoplasmic loop between the second and third transmembrane segments is pivotal in the regulation of TRESK (TWIK-related spinal cord K+ channel, K2P18.1, KCNK18). Calcineurin binds to this region and activates the channel by dephosphorylation in response ... |
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The crystal structure of plant-specific calcium-binding protein AtCBL2 in complex with the regulatory domain of AtCIPK14.
J. Mol. Biol. 377(1) , 246-57, (2008) Calcium signals mediate a multitude of plant responses to external stimuli. Calcineurin B-like (CBL) proteins and their target kinases, CBL-interacting protein kinases (CIPKs), represent important relays in plant calcium signaling. CBL interacts with CIPK thr... |
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Targeted deletion of Tssk1 and 2 causes male infertility due to haploinsufficiency
Dev. Biol. 319(2) , 211-22, (2008) Targeted deletion of Tssk1 and 2 resulted in male chimeras which produced sperm/spermatogenic cells bearing the mutant allele, however this allele was never transmitted to offspring, indicating infertility due to haploinsufficiency. Morphological defects in c... |
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A collective form of cell death requires homeodomain interacting protein kinase.
J. Cell Biol. 178(4) , 567-74, (2007) We examined post-eclosion elimination of the Drosophila wing epithelium in vivo where collective "suicide waves" promote sudden, coordinated death of epithelial sheets without a final engulfment step. Like apoptosis in earlier developmental stages, this uniqu... |
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Evolution of testis-specific kinases TSSK1B and TSSK2 in primates.
Andrology 1(1) , 160-8, (2013) The testis-specific serine/threonine protein kinases TSSK1 and TSSK2 are known to be essential for male fertility, in mice. The enzymes are present in elongating spermatids, and targeted deletion of the two genes Tssk1 and Tssk2 results in dysregulation of sp... |
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Regulation of salt and ABA responses by CIPK14, a calcium sensor interacting protein kinase in Arabidopsis.
Sci. China,. C, Life Sci. 51(5) , 391-401, (2008) Calcium and protein kinase serve as the common mediators to regulate plant responses to multiple stresses including salt and ABA stimulus. Here we reported a novel protein kinase (CIPK14) that regulated the responses to ABA treatment and salt stress in Arabid... |