PF-05089771结构式
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常用名 | PF-05089771 | 英文名 | PF 05089771 |
|---|---|---|---|---|
| CAS号 | 1430806-04-4 | 分子量 | 672.556 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C18H12Cl2FN5O3S2 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release.
PLoS ONE 11(4) , e0152405, (2016) Human genetic studies show that the voltage gated sodium channel 1.7 (Nav1.7) is a key molecular determinant of pain sensation. However, defining the Nav1.7 contribution to nociceptive signalling has been hampered by a lack of selective inhibitors. Here we re... |