乙基纤维素
乙基纤维素结构式
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常用名 | 乙基纤维素 | 英文名 | Ethyl cellulose |
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| CAS号 | 9004-57-3 | 分子量 | 448.474 | |
| 密度 | 1.45 | 沸点 | 654.2±55.0 °C at 760 mmHg | |
| 分子式 | C23H24N6O4 | 熔点 | 240-255ºC | |
| MSDS | 中文版 美版 | 闪点 | 349.5±31.5 °C |
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Coated hydralazine hydrochloride beads for sustained release after oral administration.
Drug Dev. Ind. Pharm. 39(9) , 1439-46, (2013) Hydralazine hydrochloride is an antihypertensive used alone or in combination with isosorbide nitrate for the treatment of congestive heart failure. Since control of blood pressure should be continuous, sustained release delivery of this drug is considered th... |
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Effects of molecular weight on permeability and microstructure of mixed ethyl-hydroxypropyl-cellulose films.
Eur. J. Pharm. Sci. 48(1-2) , 240-8, (2013) Films of ethyl cellulose (EC) and water-soluble hydroxypropyl cellulose (HPC) can be used for extended release coatings in oral formulations. The permeability and microstructure of free EC/HPC films with 30% w/w HPC were studied to investigate effects of EC m... |
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Mucosa-plate for direct evaluation of mucoadhesion of drug carriers.
Int. J. Pharm. 441(1-2) , 801-8, (2013) The method to prepare mucosa-plates, glass slides covalently coated with mucin, is demonstrated. The use of the plate to evaluate mucoadhesion of nanocarriers made from different four polymeric materials, N-succinylchitosan (NS-chitosan), alginate (ALG), ethy... |
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The formulation of flurbiprofen loaded microspheres using hydroxypropylmethycellulose and ethylcellulose.
Adv. Clin. Exp. Med. 22(2) , 177-83, (2013) The aim of the present work was to formulate flurbiprofen (FLB) loaded microspheres of hydroxypropylmethycellulose and ethylcellulose polymers to study the effect of different proportions of the polymer mixture on the release behavior of the drug.A series of ... |
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Formulation, in vitro drug release study and anticancer activity of 5-fluorouracil loaded gellan gum microbeads.
Acta Pol. Pharm. 70(1) , 123-7, (2013) 5-Fluorouracil loaded calcium-zinc-gellan and calcium-zinc-gellan-ethyl cellulose microbeads were successfully prepared by simple ionotropic gelation and oil in water ionotropic gelation technique, respectively. Prepared microbeads were characterized by scann... |
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Regulating drug release behavior and kinetics from matrix tablets based on fine particle-sized ethyl cellulose ether derivatives: an in vitro and in vivo evaluation.
ScientificWorldJournal 2012 , 842348, (2012) The design and fabrication of sustained/controlled release dosage forms, employing new excipients capable of extending/controlling the release of drugs from the dosage forms over prolonged periods, has worked well in achieving optimally enhanced therapeutic l... |
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Encapsulated curcumin results in prolonged curcumin activity in vitro and radical scavenging activity ex vivo on skin after UVB-irradiation.
Eur. J. Pharm. Biopharm. 82(3) , 485-90, (2012) The phytochemical curcumin possesses antioxidant activity; however, it becomes unstable after being exposed to light or heat or loses activity during storage. This is especially important when curcumin is applied to the skin within a cosmetic or pharmaceutica... |
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Study of drug release and tablet characteristics of silicone adhesive matrix tablets.
Eur. J. Pharm. Biopharm. 82(3) , 518-25, (2012) Matrix tablets of a model drug acetaminophen (APAP) were prepared using a highly compressible low glass transition temperature (T(g)) polymer silicone pressure sensitive adhesive (PSA) at various binary mixtures of silicone PSA/APAP ratios. Matrix tablets of ... |
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Low molecular mass chitosan as carrier for a hydrodynamically balanced system for sustained delivery of ciprofloxacin hydrochloride.
Acta. Pharm. 62(2) , 237-50, (2012) Chitosan has become a focus of major interest in recent years due to its excellent biocompatibility, biodegradability and non-toxicity. Although this material has already been extensively investigated in the design of different types of drug delivery systems,... |
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Investigation of a novel 3-fluid nozzle spray drying technology for the engineering of multifunctional layered microparticles.
Expert Opin. Drug Deliv. 9(12) , 1463-74, (2012) To examine the potential of a novel 3-fluid nozzle spray drying technology to formulate differentiated layered microparticles (MPs) of diclofenac sodium (DFS)/ethyl cellulose (EC).DFS/EC MPs were formulated using the inner and/or outer nozzles of a novel 3-fl... |