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(LEU15)-GASTRIN I (HUMAN)

(LEU15)-GASTRIN I (HUMAN)结构式
(LEU15)-GASTRIN I (HUMAN)结构式
品牌特惠专场
常用名 (LEU15)-GASTRIN I (HUMAN) 英文名 (Leu15)-Gastrin I (human)
CAS号 39024-57-2 分子量 2080.16000
密度 N/A 沸点 N/A
分子式 C98H126N20O31 熔点 N/A
MSDS 美版 闪点 N/A

[Syntheses of human little gastrin-I and its leucine-15, norleucine-15 and methoxinine-15 analogs].

Hoppe. Seylers. Z. Physiol. Chem. 364 , 157, (1983)

Human little gastrin-I is known to exhibit a high tendency to air-oxidation of its methionine-15 residue to the corresponding S-oxide derivative, with concomitant loss of biological activity. Since its leucine-15 analog, even if fully biologically active, dif...

Cholecystokinin(CCK)-A and CCK-B/gastrin receptors in human tumors.

Cancer Res. 57 , 1377, (1997)

Cholecystokinin (CCK)-A and CCK-B/gastrin receptors were evaluated with in vitro receptor autoradiography in 406 human tumors of various origins using a sulfated 125I-labeled CCK decapeptide analogue 125I-(D-Tyr-Gly, Nle28,3l)-CCK 26-33 and 125I-labeled Leu15...

Gastrin does not stimulate growth of the rat pancreas.

Scand. J. Gastroenterol. 31 , 404-410, (1996)

Gastrin is thought to stimulate growth of the pancreas via gastrin/cholecystokinin (CCK)-B-type receptors. The aim of the present study was to examine the trophic response of the pancreas to exogenous gastrin or to hypergastrinemia of endogenous origin and to...

ECL cells of the rat stomach: development of lipofuscin in response to sustained gastrin stimulation.

Cell Tissue Res. 291 , 315-323, (1998)

Ageing cells, especially post-mitotic cells, are known to accumulate pigments, i.e. highly electron-dense material, referred to as ceroid or lipofuscin. This material is formed as a consequence of autophagocytosis and peroxidation of the products undergoing d...

Gastrin treatment stimulates β-cell regeneration and improves glucose tolerance in 95% pancreatectomized rats.

Endocrinology 152 , 2580-2588, (2011)

β-Cell mass reduction is a central aspect in the development of type 1 and type 2 diabetes, and substitution or regeneration of the lost β-cells is a potentially curative treatment of diabetes. To study the effects of gastrin on β-cell mass in rats with 95% p...

Application of 2-chlorotrityl resin in solid phase synthesis of (Leu15)-gastrin I and unsulfated cholecystokinin octapeptide. Selective O-deprotection of tyrosine.

Int. J. Pept. Protein Res. 38(6) , 555-61, (1991)

The carboxyl terminal dipeptide amide, Fmoc-Asp-Phe-NH2, of gastrin and cholecystokinin (CCK) has been attached in high yield through its free side chain carboxyl group to the acid labile 2-chlorotrityl resin. The obtained peptide resin ester has been applied...

Gastrin receptor assay.

Meth. Enzymol. 109 , 56-64, (1985)