![]() (LEU15)-GASTRIN I (HUMAN)结构式
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常用名 | (LEU15)-GASTRIN I (HUMAN) | 英文名 | (Leu15)-Gastrin I (human) |
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CAS号 | 39024-57-2 | 分子量 | 2080.16000 | |
密度 | N/A | 沸点 | N/A | |
分子式 | C98H126N20O31 | 熔点 | N/A | |
MSDS | 美版 | 闪点 | N/A |
[Syntheses of human little gastrin-I and its leucine-15, norleucine-15 and methoxinine-15 analogs].
Hoppe. Seylers. Z. Physiol. Chem. 364 , 157, (1983) Human little gastrin-I is known to exhibit a high tendency to air-oxidation of its methionine-15 residue to the corresponding S-oxide derivative, with concomitant loss of biological activity. Since its leucine-15 analog, even if fully biologically active, dif... |
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Cholecystokinin(CCK)-A and CCK-B/gastrin receptors in human tumors.
Cancer Res. 57 , 1377, (1997) Cholecystokinin (CCK)-A and CCK-B/gastrin receptors were evaluated with in vitro receptor autoradiography in 406 human tumors of various origins using a sulfated 125I-labeled CCK decapeptide analogue 125I-(D-Tyr-Gly, Nle28,3l)-CCK 26-33 and 125I-labeled Leu15... |
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Gastrin does not stimulate growth of the rat pancreas.
Scand. J. Gastroenterol. 31 , 404-410, (1996) Gastrin is thought to stimulate growth of the pancreas via gastrin/cholecystokinin (CCK)-B-type receptors. The aim of the present study was to examine the trophic response of the pancreas to exogenous gastrin or to hypergastrinemia of endogenous origin and to... |
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ECL cells of the rat stomach: development of lipofuscin in response to sustained gastrin stimulation.
Cell Tissue Res. 291 , 315-323, (1998) Ageing cells, especially post-mitotic cells, are known to accumulate pigments, i.e. highly electron-dense material, referred to as ceroid or lipofuscin. This material is formed as a consequence of autophagocytosis and peroxidation of the products undergoing d... |
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Gastrin treatment stimulates β-cell regeneration and improves glucose tolerance in 95% pancreatectomized rats.
Endocrinology 152 , 2580-2588, (2011) β-Cell mass reduction is a central aspect in the development of type 1 and type 2 diabetes, and substitution or regeneration of the lost β-cells is a potentially curative treatment of diabetes. To study the effects of gastrin on β-cell mass in rats with 95% p... |
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Application of 2-chlorotrityl resin in solid phase synthesis of (Leu15)-gastrin I and unsulfated cholecystokinin octapeptide. Selective O-deprotection of tyrosine.
Int. J. Pept. Protein Res. 38(6) , 555-61, (1991) The carboxyl terminal dipeptide amide, Fmoc-Asp-Phe-NH2, of gastrin and cholecystokinin (CCK) has been attached in high yield through its free side chain carboxyl group to the acid labile 2-chlorotrityl resin. The obtained peptide resin ester has been applied... |
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Gastrin receptor assay.
Meth. Enzymol. 109 , 56-64, (1985)
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