(R)-N-3,5-二硝基苯甲酰基苯甘氨酸结构式
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常用名 | (R)-N-3,5-二硝基苯甲酰基苯甘氨酸 | 英文名 | (2R)-Amino(3,5-dinitrophenyl)acetic acid |
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| CAS号 | 74927-72-3 | 分子量 | 241.158 | |
| 密度 | 1.7±0.1 g/cm3 | 沸点 | 421.4±45.0 °C at 760 mmHg | |
| 分子式 | C15H11N3O7 | 熔点 | 217-218 °C (dec.) | |
| MSDS | 中文版 美版 | 闪点 | 208.6±28.7 °C |
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A screening method for chiral selectors that does not require covalent attachment.
J. Am. Chem. Soc. 128(7) , 2208-9, (2006) A high-throughput screening protocol is proposed for chiral selector discovery. It is modeled after the protocol for biological screening of candidate drugs from chemical libraries. The procedure works based on target distribution between an aqueous phase and... |
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Resolution of enantiomers of 19-hydroxyeicosatetraenoate and 18-hydroxyeicosatetraenoate by chiral phase high-performance liquid chromatography of naphthoyl ester derivatives.
J. Chromatogr. A. 526(2) , 525-9, (1990)
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QSAR of matrix metalloproteinase inhibitor N-[(substituted phenyl)sulfonyl]-N-4-nitrobenzylglycine hydroxamates using LFER model.
Drug Des. Discov. 17(4) , 315-23, (2001) QSAR analyses of matrix metalloproteinase (MMP) inhibitor N-[(substituted phenyl)sulfonyl]-N-4-nitrobenzylglycine hydroxamates, recently reported by Scozzafava and Supuran, have been attempted using linear free energy related (LFER) model of Hansch to explore... |
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Capillary electrophoresis with (R)-(--)-N-(3,5-dinitrobenzoyl)-alpha-phenylglycine as chiral selector for separation of albendazole sulfoxide enantiomers and their analysis in human plasma.
J. Pharm. Biomed. Anal. 27(3-4) , 555-67, (2002) The electrokinetic separation and analysis of the enantiomers of albendazole sulfoxide (ABZSO), a sulfoxide with a sulfur stereogenic center hepatically formed during therapy with the anthelmintic drug albendazole (ABZ), is reported. Using aqueous or nonaqueo... |
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Capillary zone electrophoresis study of naphthylethylcarbamoylated beta-cyclodextrins.
Anal. Chem. 67(1) , 19-25, (1995) Regiospecifically monosubstituted 1-(1-naphthyl)ethylcarbamoylated beta-cyclodextrins (NEC-beta-CDs) were successfully employed as chiral additives in capillary zone electrophoresis (CZE) to achieve chiral separation of N-(3,5-dinitrobenzoyl)phenylglycine (3,... |
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Solvation of phenylglycine- and leucine-derived chiral stationary phases: molecular dynamics simulation study.
J. Phys. Chem. B 112(41) , 13022-37, (2008) A theoretical study of the solvation of ( R)- N-(3,5-dinitrobenzoyl)phenylglycine- and ( R)- N-(3,5-dinitrobenzoyl)leucine-derived chiral stationary phases (CSPs) is presented. Semiflexible models of the chiral selectors are prepared from B3LYP/6-311G** calcu... |
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Direct separation of non-K-region mono-ol and diol enantiomers of phenanthrene, benz[a]anthracene, and chrysene by high-performance liquid chromatography with chiral stationary phases.
J. Chromatogr. A. 371 , 211-25, (1986) The direct separation of 26 bay region and non-bay region mono-ol and diol enantiomers of phenanthrene, benz[a]anthracene, and chrysene was compared by high-performance liquid chromatography on commercially available columns, packed with gamma-aminopropylsila... |
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Elution order-absolute configuration relationship of K-region dihydrodiol enantiomers of benz[a]anthracene derivatives in chiral stationary phase high-performance liquid chromatography.
J. Chromatogr. A. 371 , 195-209, (1986) The direct resolution of K-region cis- and trans-dihydrodiol enantiomers of 14 unsubstituted and methyl- and bromo-substituted benz[a]anthracene (BA) derivatives was investigated by high-performance liquid chromatography with commercially available columns, p... |