环芬尼结构式
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常用名 | 环芬尼 | 英文名 | Cyclofenil |
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| CAS号 | 2624-43-3 | 分子量 | 364.434 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 509.0±30.0 °C at 760 mmHg | |
| 分子式 | C23H24O4 | 熔点 | 133-136°C | |
| MSDS | 美版 | 闪点 | 254.8±23.0 °C |
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A misguided 'pill in the pocket' approach with flecainide leading to cardiac arrest.
BMJ Case Rep. 2012 , doi:10.1136/bcr-2012-006868, (2012)
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Exploration of the bicyclo[3.3.1]nonane system as a template for the development of new ligands for the estrogen receptor.
Bioorg. Med. Chem. Lett. 13(24) , 4485-8, (2003) Three novel structural motifs based on a bicyclo [3.3.1]nonane template were examined as new ligands for estrogen receptor (ER). Type III compounds emerged as the most promising leads for developing high-affinity ER ligands, but they showed little selectivity... |
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Synthesis of new carbon-11 labeled cyclofenil derivatives for PET imaging of breast cancer estrogen receptors.
Appl. Radiat. Isot. 66(4) , 523-9, (2008) Carbon-11 labeled cyclofenil derivatives, [(11)C]methyl-2-{4-[bis(4-hydroxyphenyl)methylene]cyclohexyl}acetate ([(11)C]16a), [(11)C]methyl-4-[bis(4-hydroxyphenyl)methylene]cyclohexanecarboxylate ([(11)C]16b), [(11)C]methyl-2-{3-[bis(4-hydroxyphenyl)methylene]... |
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Synthesis and biodistribution of fluorine-18-labeled fluorocyclofenils for imaging the estrogen receptor.
Nucl. Med. Biol. 34(4) , 383-90, (2007) C4-[18F]Fluorocyclofenil ([18F]FCF, 6) and C3-[18F]fluoroethylcyclofenil ([18F]FECF, 9), two high-affinity nonsteroidal estrogens, were prepared and investigated as potential agents for imaging estrogen receptors (ERs) in breast tumors. Both of these compound... |
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Retrograde trafficking of both Golgi complex and TGN markers to the ER induced by nordihydroguaiaretic acid and cyclofenil diphenol.
J. Cell Sci. 111 ( Pt 7) , 951-65, (1998) Previous studies have shown that the Golgi stack and the trans-Golgi network (TGN) may play a role in capturing escaped resident endoplasmic reticulum (ER) proteins, and directing their retrograde transport back to that organelle. Whether this retrograde move... |
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The effects of clomiphene citrate and cyclofenil on cervical mucus volume and receptivity over the periovulatory period.
Fertil. Steril. 59(1) , 125-9, (1993) To determine the effects of clomiphene citrate (CC) and cyclofenil on cervical mucus (CM) volume and receptivity sampled serially over the periovulatory period.Using prospective luteinizing hormone (LH) timing CM volume and receptivity were compared in standa... |
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Nonclassical SNAPFL analogue as a Cy5 resonance energy transfer partner.
Org. Lett. 10(21) , 4931-4, (2008) We have synthesized a new SNAPFL analogue (1) that exhibits a large Stokes shift (78 nm) (abs. 542 nm, em. 620 nm) and a good quantum yield. Because of the large overlap between the emission spectrum of 1 and the absorption spectrum of Cy5, 1 functions well a... |
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Acute hepatitis induced by cyclofenil: a case report.
Ital. J. Gastroenterol. 24(2) , 77-8, (1992) The case of a 47-year old woman suffering from acute hepatitis caused by cyclofenil, a drug proposed for the treatment of anovulation and scleroderma, is presented. Hepatitis developed seven weeks after the beginning of administration of the drug and its cour... |
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Fluorimetric determination of cyclofenil using photochemical derivatization.
Talanta 74(5) , 1442-9, (2008) In this work, a fluorimetric approach for the determination of cyclofenil, 4-4'-(cyclohexylidenemethylene)bis(phenylacetate), is presented. The method was based on the intense fluorescence (250/410 nm) observed after a UV photochemical treatment of cyclofenil... |
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Effects of cyclofenil diphenol, an agent which disrupts Golgi structure, on proteoglycan synthesis in chondrocytes.
Biochem. J. 281 ( Pt 2) , 525-31, (1992) 1. Cyclofenil diphenol (F6060), a weak non-steroidal oestrogen, was shown previously to inhibit [35S]proteoglycan synthesis [Mason, Lineham, Phillipson & Black (1984) Biochem. J. 223, 401-412] and to induce fragmentation of the Golgi apparatus into small vesi... |