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白僵菌素

白僵菌素结构式
白僵菌素结构式
品牌特惠专场
常用名 白僵菌素 英文名 beauvericin
CAS号 26048-05-5 分子量 783.949
密度 1.1±0.1 g/cm3 沸点 975.6±65.0 °C at 760 mmHg
分子式 C45H57N3O9 熔点 93-94℃
MSDS 中文版 美版 闪点 543.8±34.3 °C

Toxicity induced by F. poae-contaminated feed and the protective effect of Montmorillonite supplementation in broilers.

Food Chem. Toxicol. 74 , 120-30, (2014)

The T-2 and HT-2 toxins, the main metabolites of Fusarium poae, induce toxicity in broilers and accumulate in tissues. Consequently, during the breeding process of broilers, diets are frequently supplemented with physical adsorbents to protect birds against t...

Development and validation of an UHPLC-MS/MS method for the determination of mycotoxins in grass silages.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 32 , 2101-12, (2015)

An ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) multi-mycotoxin analytical method was developed to simultaneously identify and quantify 20 mycotoxins in grass silages, inclusive of mycotoxins that are currently regulated...

Determination of the Mycotoxin Content in Distiller's Dried Grain with Solubles Using a Multianalyte UHPLC-MS/MS Method.

J. Agric. Food Chem. 63 , 9441-51, (2015)

There are more than 300 potential mycotoxins that can contaminate food and feed and cause adverse effects in humans and animals. The data on the co-occurrence of mycotoxins in novel animal feed materials, such as distiller's dried grain with solubles (DDGS), ...

Automated identification of depsipeptide natural products by an informatic search algorithm.

ChemBioChem. 16(2) , 223-7, (2015)

Nonribosomal depsipeptides are a class of potent microbial natural products, which include several clinically approved pharmaceutical agents. Genome sequencing has revealed a large number of uninvestigated natural-product biosynthetic gene clusters. However, ...

Disturbance of antioxidant capacity produced by beauvericin in CHO-K1 cells.

Toxicol. Lett. 226(3) , 337-42, (2014)

Glutathione (GSH) levels, glutathione peroxidase (GPx), glutathione reductase (GR) and glutathione-S-transferase (GST) as antioxidant defense system were evaluated in CHO-K1 cells after beauvericin (BEA) exposure. The effect of N-acetyl-cysteine (NAC) pre-tre...

Study of the cytotoxic activity of beauvericin and fusaproliferin and bioavailability in vitro on Caco-2 cells.

Food Chem. Toxicol. 50(7) , 2356-61, (2012)

Beauvericin (BEA) is a cyclohexadepsipeptide mycotoxin which has insecticidal properties and produces cytotoxic effects in mammalian cells. Fusaproliferin (FUS) is a mycotoxin that has toxic activity against brine shrimp, insect cells, and teratogenic effects...

Overview of analytical methods for beauvericin and fusaproliferin in food matrices.

Anal. Bioanal. Chem 395(5) , 1253-60, (2009)

In recent years consumers and the scientific community have become increasingly interested in food safety, making it a major focus among the objectives of the international institutions responsible for food safety monitoring, e.g. the European Union or the EF...

In vitro chemoenzymatic and in vivo biocatalytic syntheses of new beauvericin analogues.

Chem. Commun. (Camb.) 48(45) , 5674-6, (2012)

New beauvericins have been synthesized using the nonribosomal peptide synthetase BbBEAS from the entomopathogenic fungus Beauveria bassiana. Chemical diversity was generated by in vitro chemoenzymatic and in vivo whole cell biocatalytic syntheses using either...

Characterization and mycotoxigenic potential of Fusarium species in freshly harvested and stored sugar beet in Europe.

Phytopathology 101(11) , 1330-7, (2011)

Based on a 2-year field trial at two locations in Lower Saxony (Germany), 395 Fusarium isolates belonging to 13 species were collected from more than 3,000 sugar beet roots that were apparently healthy at harvest. In a comparative screen, subsamples were anal...

Modeling of Fusarium redolens Dzf2 mycelial growth kinetics and optimal fed-batch fermentation for beauvericin production.

J. Ind. Microbiol. Biotechnol. 38(9) , 1187-92, (2011)

Beauvericin (BEA) is a cyclic hexadepsipeptide mycotoxin with notable phytotoxic and insecticidal activities. Fusarium redolens Dzf2 is a highly BEA-producing fungus isolated from a medicinal plant. The aim of the current study was to develop a simple and val...