N-苄氧羰基甘氨酰-L-脯氨酸
N-苄氧羰基甘氨酰-L-脯氨酸结构式
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常用名 | N-苄氧羰基甘氨酰-L-脯氨酸 | 英文名 | Z-Gly-Pro-OH |
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| CAS号 | 1160-54-9 | 分子量 | 306.31400 | |
| 密度 | 1.335g/cm3 | 沸点 | 579.8ºC at 760mmHg | |
| 分子式 | C15H18N2O5 | 熔点 | 155-158 °C | |
| MSDS | 中文版 美版 | 闪点 | 304.4ºC |
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Determination of (R)- and (S)-propranolol in plasma by high-performance liquid chromatography using N-benzoxycarbonylglycyl-L-proline as chiral selector in the mobile phase.
J. Chromatogr. A. 494 , 157-71, (1989) A normal-phase chromatographic method for the determination of (R)- and (S)-propranolol in plasma is described. The chiral separation is performed by adding an optically active complexing agent, N-benzoxycarbonylglycyl-L-proline, to the mobile phase (dichloro... |
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Enantioselective high-performance liquid chromatographic determination of (SR)- and (RS)-mefloquine in plasma using N-benzyloxycarbonyl-glycyl-L-proline as chiral counter ion.
J. Chromatogr. A. 620(2) , 217-24, (1993) A stereoselective HPLC method is described for the determination of (SR)- and (RS)-mefloquine in plasma. The direct chiral separation is carried out on a Hypercarb-S column (porous graphitised carbon) with N-benzyloxycarbonyl-glycyl-L-proline (L-ZGP) as a chi... |
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Chiral separation of amines with N-benzoxycarbonylglycyl-L-proline as selector in non-aqueous capillary electrophoresis using methanol and 1,2-dichloroethane in the background electrolyte.
J. Chromatogr. A. 984(2) , 261-71, (2003) N-Benzoxycarbonylglycyl-L-proline (L-ZGP) has been introduced as a chiral selector for enantioseparation of amines in non-aqueous capillary electrophoresis. Methanol mixed with different proportions of dichloromethane, 1,2-dichloroethane or 2-propanol contain... |
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Enantiomeric separation of basic drugs using N-benzyloxycarbonylglyclyl-L-proline as counter ion in methanol.
J. Chromatogr. A. 705(2) , 275-87, (1995) Direct separation of enantiomeric amines using mainly N-benzyloxycarbonylglycyl-L-proline (L-ZGP) but also N-benzyloxycarbonylglyclglcyl-L-proline (L-ZGGP) as the chiral counter ion in methanol is described. The solid phase was Hypercarb porous graphitic carb... |
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Possible involvement of aminopeptidase, an ecto-enzyme, in the inactivation of bradykinin by intact neutrophils.
Biochim. Biophys. Acta 847(1) , 67-76, (1985) The subcellular localization of the bradykinin-inactivating activity was studied using guinea-pig neutrophils and the following results were obtained. The bradykinin-inactivating activities were found to be present in the cytosol and membrane fractions but no... |
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Structures of prolyl oligopeptidase substrate/inhibitor complexes. Use of inhibitor binding for titration of the catalytic histidine residue.
J. Biol. Chem. 276(2) , 1262-6, (2001) Structure determination of the inactive S554A variant of prolyl oligopeptidase complexed with an octapeptide has shown that substrate binding is restricted to the P4-P2' region. In addition, it has revealed a hydrogen bond network of potential catalytic impor... |