氘代二甲基亚砜
氘代二甲基亚砜结构式
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常用名 | 氘代二甲基亚砜 | 英文名 | DIMETHYL SULFOXIDE-D6 |
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| CAS号 | 2206-27-1 | 分子量 | 84.170 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 189.0±9.0 °C at 760 mmHg | |
| 分子式 | C2D6OS | 熔点 | 20-56ºC | |
| MSDS | 中文版 美版 | 闪点 | 85.0±0.0 °C |
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Permeation of Dopamine Sulfate through the Blood-Brain Barrier.
PLoS ONE 10 , e0133904, (2015) Dopamine sulfate (DA-3- and DA-4-S) have been determined in the human brain, but it is unclear whether they are locally formed in the central nervous system (CNS), or transported into the CNS from peripheral sources. In the current study, permeation of the bl... |
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Lipophilic prodrugs of nucleoside triphosphates as biochemical probes and potential antivirals.
Nat. Commun. 6 , 8716, (2015) The antiviral activity of nucleoside reverse transcriptase inhibitors is often limited by ineffective phosphorylation. We report on a nucleoside triphosphate (NTP) prodrug approach in which the γ-phosphate of NTPs is bioreversibly modified. A series of TriPPP... |
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Synthesis, cytotoxicity and antiviral evaluation of new series of imidazo[4,5-g]quinoline and pyrido[2,3-g]quinoxalinone derivatives.
Eur. J. Med. Chem. 105 , 63-79, (2015) Linear aromatic N-tricyclic compounds with promising antiviral activity and minimal cytotoxicity were prepared and analyzed in the last years. Specifically, the pyrido[2,3-g]quinoxalinone nucleus was found endowed with high potency against several pathogenic ... |
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Sulfation modulates the cell uptake, antiradical activity and biological effects of flavonoids in vitro: An examination of quercetin, isoquercitrin and taxifolin.
Bioorg. Med. Chem. 23 , 5402-9, (2015) Quercetin 3'-O-sulfate is one of the main metabolites of the natural flavonoid quercetin in humans. This study was designed to prepare quercetin 3'-O-sulfate (1), isoquercitrin 4'-O-sulfate (2) and taxifolin 4'-O-sulfate (3) by the sulfation of quercetin, iso... |
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Curdlan-Conjugated PLGA Nanoparticles Possess Macrophage Stimulant Activity and Drug Delivery Capabilities.
Pharm. Res. 32 , 2713-26, (2015) There is significant interest in the application of nanoparticles to deliver immunostimulatory signals to cells. We hypothesized that curdlan (immune stimulating polymer) could be conjugated to PLGA and nanoparticles from this copolymer would possess immunost... |
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Chirality of Single-Handed Twisted Titania Tubular Nanoribbons Prepared Through Sol-gel Transcription.
Chirality 27 , 543-50, (2015) Single-handed twisted titania tubular nanoribbons were prepared through sol-gel transcription using a pair of enantiomers. Handedness was controlled by that of the template. The obtained samples were characterized using field-emission electron microscopy, tra... |
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Antitumor activity of a 2-pyridinecarboxaldehyde 2-pyridinecarboxylic acid hydrazone copper complex and the related mechanism.
Oncol. Rep. 34 , 1311-8, (2015) In the present study, 2-pyridinecarboxaldehyde 2-pyridinecarboxylic acid hydrazone (PPAH) was prepared and its antitumor activity was evaluated. The inhibition of proliferation of PPAH against the HepG2 and HCT-116 cell lines was less effective, yet in the pr... |
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Synthesis and analysis of the anticancer activity of platinum(II) complexes incorporating dipyridoquinoxaline variants.
Dalton Trans. 43(41) , 15566-75, (2014) Eight platinum(II) complexes with anticancer potential have been synthesised and characterised. These complexes are of the type [Pt(I(L))(A(L))](2+), where I(L) is either dipyrido[3,2-f:2',3'-h]quinoxaline (dpq) or 2,3-dimethyl-dpq (23Me2dpq) and A(L) is one ... |
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Small expression tags enhance bacterial expression of the first three transmembrane segments of the apelin receptor.
Biochem. Cell Biol. 92(4) , 269-78, (2014) G-protein coupled receptors (GPCRs) are inherently dynamic membrane protein modulators of various important cellular signaling cascades. The apelin receptor (AR or APJ) is a class A GPCR involved in numerous physiological processes, implicated in angiogenesis... |
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Enzyme-assisted supercritical carbon dioxide extraction of black pepper oleoresin for enhanced yield of piperine-rich extract.
J. Biosci. Bioeng. 120 , 17-23, (2015) Black pepper (Piper nigrum L.), the King of Spices is the most popular spice globally and its active ingredient, piperine, is reportedly known for its therapeutic potency. In this work, enzyme-assisted supercritical carbon dioxide (SC-CO2) extraction of black... |