伊洛马司他结构式
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常用名 | 伊洛马司他 | 英文名 | GM 6001 |
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CAS号 | 142880-36-2 | 分子量 | 388.461 | |
密度 | 1.228±0.06 g/cm3 | 沸点 | N/A | |
分子式 | C20H28N4O4 | 熔点 | N/A | |
MSDS | 中文版 美版 | 闪点 | N/A |
Inhibition of human skin fibroblast collagenase, thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids.
Biochemistry 31 , 7152, (1992) The hydroxamic acid HONHCOCH2CH(i-Bu)CO-L-Trp-NHMe, isomer 6A (GM 6001), inhibits human skin fibroblast collagenase with Ki of 0.4 nM using the synthetic thiol ester substrate Ac-Pro-Leu-Gly-SCH(i-Bu)CO-Leu-Gly-OEt at pH 6.5. The other isomer, 6B, which has t... |