2-甲基-2-丙烯酸的均聚物

Pharmazie 69(7) , 512-7, (2014)

To develop a novel triamcinolone acetonide (TAA)-loaded spray for the treatment of stomatitis, several spray solutions were prepared using various amounts of TAA, Eudragit L100 (Eudragit L) and PEG 400, and 100 ml ethanol. Their viscosity and spraying potenti...

Drug Dev. Ind. Pharm. 39(2) , 352-62, (2013)

Gliclazide (GLZ)-loaded microparticles made with a polymeric blend were prepared by a solvent evaporation technique. Organic solutions of two polymers, poly(ε-caprolactone) (PCL) and Eudragit RS (E RS) or ethyl cellulose (EC), in different weight ratios, and ...

Bioengineered 3(5) , 286-8, (2012)

Affinity precipitation is a non-chromatographic method which is useful for purification and refolding of proteins. Quite often, a stimuli-sensitive polymer can be identified which selectively binds to the desired protein. For separation, the protein can be re...

Expert Opin. Drug Deliv. 10(6) , 741-6, (2013)

Alendronate sodium (ALS) is the most common drug used for the treatment of osteoporosis. The challenges facing ALS use include: very poor oral bioavailability (0.6%), esophageal ulcers, and complicated instructions for its use. The objective of this research ...

Expert Opin. Drug Deliv. 10(9) , 1179-91, (2013)

The objective of the study was to investigate the effect of iron oxide in the development of mucoadhesive tablets of cinnarizine using Eudragit RLPO polymer. A simplex lattice design was employed for optimizing the drug delivery system.Different concentration...

J. Biomed. Nanotechnol. 9(4) , 590-600, (2013)

In this investigation, novel cationic thiomer, Thiolated polydimethylaminoethylmethacrylate (PDCys) is synthesised and the feasibility of PDCys sub-microparticles as oral insulin delivery carriers is evaluated in vitro. The presence of both positive charge an...

Acta. Pharm. 62(1) , 71-82, (2012)

Sustained release (SR) dosage forms enable prolonged and continuous deposition of the drug in the gastrointestinal (GI) tract and improve the bioavailability of medications characterized by a narrow absorption window. In this study, a new strategy is proposed...

J. Chromatogr. A. 1365 , 219-25, (2014)

• Monomer ratio affected microstructure and EKC properties of polymeric aggregations. • Low CACs could be gained when hydrophobic monomer ratio increased. • Improve separation window and methylene selectivity by increasing hydrophobic monomer ratio. • LSER an...

Eur. J. Pharm. Biopharm. 82(3) , 491-7, (2012)

VarioSol® is an innovative, solvent-free technology able to produce microparticles exploiting near-critical CO(2) properties as spraying and cooling agent. The aim of the present work was to evaluate the feasibility to produce in a single processing step by V...

J. Drug Target. 20(8) , 703-14, (2012)

The intent of the present investigation is to develop colon targeted compression coated flurbiprofen pulsatile release tablets that retard the drug release in the upper gastro intestinal system but progressively release in the colon.Flurbiprofen core tablets ...