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2-氯-4,6-二氨-1,3,5-三嗪

2-氯-4,6-二氨-1,3,5-三嗪结构式
2-氯-4,6-二氨-1,3,5-三嗪结构式
品牌特惠专场
常用名 2-氯-4,6-二氨-1,3,5-三嗪 英文名 Deethyldeisopropylatrazine
CAS号 3397-62-4 分子量 145.550
密度 1.7±0.1 g/cm3 沸点 487.9±28.0 °C at 760 mmHg
分子式 C3H4ClN5 熔点 >320 °C(lit.)
MSDS 中文版 美版 闪点 248.9±24.0 °C

Alteration of catecholamines in pheochromocytoma (PC12) cells in vitro by the metabolites of chlorotriazine herbicide.

Toxicol. Sci. 59(1) , 127-37, (2001)

The effects of four major chlorotriazine metabolites on the constitutive synthesis of the catecholamines dopamine (DA) and norepinephrine (NE) were examined, using undifferentiated PC12 cells. NE release and intracellular DA and NE concentrations were quantif...

Pubertal development in female Wistar rats following exposure to propazine and atrazine biotransformation by-products, diamino-S-chlorotriazine and hydroxyatrazine.

Toxicol. Sci. 76(1) , 190-200, (2003)

We showed previously that the chlorotriazine herbicide, atrazine (ATR), delays the onset of pubertal development in female rats. ATR and its biotransformation by-products are present in soil and groundwater. Since current maximum contaminant levels are set on...

Oral absorption and oxidative metabolism of atrazine in rats evaluated by physiological modeling approaches.

Toxicology 240(1-2) , 1-14, (2007)

Atrazine (ATRA) is metabolized by cytochrome P450s to the chlorinated metabolites, 2-chloro-4-ethylamino-6-amino-1,3,5-triazine (ETHYL), 2-chloro-4-amino-6-isopropylamino-1, 3, 5-triazine (ISO), and diaminochlorotriazine (DACT). Here, we develop a set of phys...

Utilization of chlorinated s-triazines by a new strain of Klebsiella pneumoniae.

Appl. Microbiol. Biotechnol. 42(5) , 763-8, (1995)

A bacterium utilizing 2-chloro-4,6-diamino-s-triazine (CAAT) as sole nitrogen source was isolated under a N2-free atmosphere and identified as Klebsiella pneumoniae. Concomitant to CAAT degradation the protein content increased and chloride was released into ...

Determination of herbicides and a metabolite in human urine by liquid chromatography-electrospray ionization mass spectrometry.

J. Chromatogr. A. 987(1-2) , 375-80, (2003)

A method was developed to determine simazine, atrazine and their metabolite, 2-chloro-4,6-diamino-1,3,5-triazine, in urine. The presence of these herbicides in urine may reflect possible exposure to pesticides. Sample preparation involved protein precipitatio...

Identification of a novel hemoglobin adduct in Sprague Dawley rats exposed to atrazine.

Chem. Res. Toxicol. 19(5) , 692-700, (2006)

Atrazine (2-chloro-4-[ethylamino]-6-[isopropylamino]-1,3,5-triazine) is one of the most commonly used herbicides in North America and is frequently detected in ground and surface waters. This research investigated possible covalent modifications of hemoglobin...

Enzymatic degradation of chlorodiamino-s-triazine.

Appl. Environ. Microbiol. 68(9) , 4672-5, (2002)

2-Chloro-4,6-diamino-s-triazine (CAAT) is a metabolite of atrazine biodegradation in soils. Atrazine chlorohydrolase (AtzA) catalyzes the dechlorination of atrazine but is unreactive with CAAT. In this study, melamine deaminase (TriA), which is 98% identical ...