胃泌素,鼠结构式
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常用名 | 胃泌素,鼠 | 英文名 | Gastrin I rat |
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| CAS号 | 81123-06-0 | 分子量 | 2126.28000 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C94H128N22O31S2 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Processing of the gastrin precursor. Modulation of phosphorylated, sulfated, and amidated products.
J. Biol. Chem. 265(35) , 21476-81, (1990) Post-translational processing of the precursor for rat gastrin yields products that include peptides phosphorylated at Ser96, amidated at Phe92, and sulfated at Tyr87 or Tyr103. The phosphorylation site is immediately adjacent to the processing point that giv... |
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Gastrin-producing endocrine cells: a novel source of histamine in the rat stomach.
Endocrinology 139(10) , 4404-15, (1998) Gastrin and histamine both potently stimulate secretion of acid into the gastric lumen. How these agents interact and how their release is controlled is poorly understood. Therefore, we decided to look for histamine in the antral portion of the rat stomach wh... |
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Histidine decarboxylase expression and histamine metabolism in gastric oxyntic mucosa during hypergastrinemia and carcinoid tumor formation.
Endocrinology 137(10) , 4435-42, (1996) Histamine is an important stimulator of gastric acid secretion. In experimental animals, inhibition of acid secretion by long term histamine2 receptor blockade causes hypergastrinemia, proliferation of enterochromaffin-like (ECL) cells, and formation of hista... |
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Gastrin upregulates the prosurvival factor secretory clusterin in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats.
Am. J. Physiol. Gastrointest. Liver Physiol. 302(1) , G21-33, (2012) We show that the gastric hormone gastrin induces the expression of the prosurvival secretory clusterin (sCLU) in rat adenocarcinoma cells. Clusterin mRNA was still upregulated in the presence of the protein synthesis inhibitor cycloheximide, although at a low... |
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Mechanisms for regulation of gastrin and somatostatin release from isolated rat stomach during gastric distention.
World J. Gastroenterol. 9(1) , 129-33, (2003) To investigate the intragastric mechanisms for regulation of gastric neuroendocrine functions during gastric distention in isolated vascularly perfused rat stomach.Isolated vascularly perfused rat stomach was prepared, then the gastric lumen was distended wit... |
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Gastrin enhances gastric mucosal integrity through cyclooxygenase-2 upregulation in rats.
Am. J. Physiol. Gastrointest. Liver Physiol. 283(6) , G1368-78, (2002) Gastrin, PGs, and growth factors have important roles in maintaining gastrointestinal mucosal integrity. Cyclooxygenases (COX-1 and COX-2) are the key enzymes involved in PG synthesis. This study aimed to clarify the mechanisms of gastric mucosal protection b... |
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Rat gastrin's amino acid sequence determined from the nucleotide sequence of the mRNA.
Peptides 3 , 693-696, (1982)
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