N-乙酰-L-天门冬酰胺结构式
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常用名 | N-乙酰-L-天门冬酰胺 | 英文名 | Na-Acetyl-L-asparagine |
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| CAS号 | 4033-40-3 | 分子量 | 174.155 | |
| 密度 | 1.3±0.1 g/cm3 | 沸点 | 588.7±45.0 °C at 760 mmHg | |
| 分子式 | C6H10N2O4 | 熔点 | 168-170ºC | |
| MSDS | 中文版 美版 | 闪点 | 309.8±28.7 °C |
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Evaluation of MR markers that predict survival in patients with newly diagnosed GBM prior to adjuvant therapy.
J. Neurooncol. 91(1) , 69-81, (2009) Purpose Glioblastoma Multiforme (GBM) is the most common and lethal primary brain tumor in adults. The goal of this study was to test the predictive value of MR parameters in relation to the survival of patients with newly diagnosed GBM who were scanned prior... |
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The apparent dependence of the diffusion coefficient of N-acetylaspartate upon magnetic field strength: evidence of an interaction with NMR methodology.
NMR Biomed. 16(8) , 468-74, (2003) An inverse relationship between applied magnetic field strength and the apparent diffusion coefficient (ADC) of several important brain metabolites including N-acetyl-l-aspartate (NAA), choline and creatine, measured in vivo using proton magnetic resonance sp... |
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Liquid chromatographic-mass spectrometric analysis of N-acetylamino acids in human urine.
J. Chromatogr. B, Biomed. Appl. 657(1) , 15-21, (1994) Liquid chromatography-atmospheric pressure chemical-ionization mass spectrometry (LC-APCI-MS) was used for the analysis of N-acetylamino acids that could not be determined with an amino acid analyzer. LC-APCI-MS could directly detect the protonated molecular ... |
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Murine aspartoacylase: cloning, expression and comparison with the human enzyme.
Brain Res. Mol. Brain Res. 77(2) , 285-9, (2000) Canavan disease is caused by mutations in aspartoacylase, the enzyme that degrades N-acetylaspartate (NAA) into acetate and aspartate. Murine aspartoacylase (mASPA) was cloned using sequence information from mouse expressed sequence tags homologous to the hum... |
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[Regulatory role of the excitatory amino acid system in the neuromediator response of the hypothalamus to stress].
Dokl. Akad. Nauk. 351(4) , 567-70, (1996)
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[Effect of hyperbaric oxygenation on N-acetyl-L-asparaginic acid metabolism in different cerebral areas].
Ukr. Biokhim. Zh. 52(5) , 564-8, (1980) The content of N-acetyl-l-asparaginic acid, CoA, CoASAc and the N-acetylaspartate amunohydrolase activity was determined in cerebral areas of rats at the normal level and at different stages of oxygen poisoning. At the preconvulsive stage of the oxygen poison... |
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[The effect of early visual deprivation on the level of N-acetyl-1-asparaginic acid and the activity of phosphate-activated glutaminase in visual analyzer structures and various regions of the dog cerebral cortex and cerebellum].
Vopr. Med. Khim. 37(4) , 37-40, (1991) Under conditions of 45-days visual deprivation content of N-acetyl-L-aspartic acid was considerably increased in visual cortex (field 17) tissues and decreased in the superior colliculus and exterior geniculate body. At the same time, content of N-acetyl-L-as... |
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Stripe-like increase of rCBV beyond the visible border of glioblastomas: site of tumor infiltration growing after neurosurgery.
J. Neurooncol. 103(3) , 575-84, (2011) We observed a stripe-like pattern of regional cerebral blood volume (rCBV) increase in a defined region adjacent to the contrast enhancement (CE) on MRI of glioblastomas (GBM) that we defined as the "striate sign" (SS). We hypothesized that the SS marks infil... |
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Proton magnetic resonance spectroscopy in children with spastic diplegia.
Neurosci. Lett. 363(1) , 62-4, (2004) The objective of this prospective study was the application of proton magnetic resonance spectroscopy in children with spastic diplegia (SD) to determine the metabolite profile of SD children in the left basal ganglia, and to assess the relationship of this p... |
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31P-MR spectroscopy in monozygotic twins discordant for schizophrenia or schizoaffective disorder.
Schizophr. Res. 134(2-3) , 296-7, (2012)
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