甲基纤维素
甲基纤维素结构式
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常用名 | 甲基纤维素 | 英文名 | methyl cellulose |
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| CAS号 | 9004-67-5 | 分子量 | 658.72900 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C29H54O16 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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In Vivo Profiling Reveals a Competent Heat Shock Response in Adult Neurons: Implications for Neurodegenerative Disorders.
PLoS ONE 10 , e0131985, (2015) The heat shock response (HSR) is the main pathway used by cells to counteract proteotoxicity. The inability of differentiated neurons to induce an HSR has been documented in primary neuronal cultures and has been proposed to play a critical role in ageing and... |
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Compounded preparations with nystatin for oral and oromucosal administration.
Acta Pol. Pharm. 70(4) , 759-62, (2013) Therapy of oral, esophageal and gastrointestinal candidiasis is still a common problem that can be solved by an administration of antimycotics. Major disadvantage of registered commercial antifungal medicinal products is their price, so the health care system... |
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Curcumin amorphous solid dispersions: the influence of intra and intermolecular bonding on physical stability.
Pharm. Dev. Technol. 19(8) , 976-86, (2014) We have investigated the physical stability of amorphous curcumin dispersions and the role of curcumin-polymer intermolecular interactions in delaying crystallization. Curcumin is an interesting model compound as it forms both intra and intermolecular hydroge... |
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A new self-microemulsifying mouth dissolving film to improve the oral bioavailability of poorly water soluble drugs.
Drug Dev. Ind. Pharm. 39(9) , 1284-90, (2013) A new self-microemulsifying mouth dissolving film (SMMDF) for poorly water-soluble drugs such as indomethacin was developed by incorporating self-microemulsifying components with solid carriers mainly containing microcrystalline cellulose, low-substituted hyd... |
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Formulation and drying of miconazole and itraconazole nanosuspensions.
Int. J. Pharm. 443(1-2) , 209-20, (2013) Miconazole and itraconazole possess adequate membrane permeability, but only slight water solubility, which limits their bioavailability and antifungal effect. To increase their dissolution rate, the compounds were nanoground by media milling to produce nanos... |
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Note on the formulation of thermosensitive and mucoadhesive vaginal hydrogels containing the miniCD4 M48U1 as anti-HIV-1 microbicide.
Int. J. Pharm. 454(2) , 649-52, (2013) The miniCD4 M48U1 was formulated into thermosensitive and mucoadhesive pluronic(®) hydrogels as anti-HIV-1 microbicide. The release kinetics of M48U1 from F127/HPMC (20/1 wt%) and F127/F68/HPMC (22.5/2.5/1 wt%) studied during 24h by using Franz diffusion cell... |
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Supersaturatable formulations for the enhanced oral absorption of sirolimus.
Int. J. Pharm. 445(1-2) , 108-16, (2013) The purpose of this study was to develop supersaturatable formulations for the enhanced solubility and oral absorption of sirolimus. Supersaturatable formulations of hydrophilic polymers and/or surfactants were screened by formulation screening, which is base... |
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Physical-mechanical and antimicrobial properties of nanocomposite films with pediocin and ZnO nanoparticles.
Carbohydr. Polym. 94(1) , 199-208, (2013) This work aimed to develop nanocomposite films of methyl cellulose (MC) incorporated with pediocin and zinc oxide nanoparticles (nanoZnO) using the central composite design and response surface methodology. This study evaluated film physical-mechanical proper... |
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Improved human bioavailability of vemurafenib, a practically insoluble drug, using an amorphous polymer-stabilized solid dispersion prepared by a solvent-controlled coprecipitation process.
J. Pharm. Sci. 102(3) , 967-81, (2013) The present work deals with improving the solubility of vemurafenib, a practically insoluble drug, by converting it into an amorphous-solid dispersion using a solvent-controlled precipitation process. The dispersion containing vemurafenib and hypromellose ace... |
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Investigation of griseofulvin and hydroxypropylmethyl cellulose acetate succinate miscibility in ball milled solid dispersions.
Int. J. Pharm. 443(1-2) , 95-102, (2013) Solid dispersions of varying weight ratios compositions of the nonionic drug, griseofulvin and the hydrophilic, anionic polymer, hydroxylpropylmethyl cellulose acetate succinate, have been prepared by ball milling and the resulting samples characterized using... |