辛卡利特
辛卡利特结构式
|
常用名 | 辛卡利特 | 英文名 | Cholecystokinin Octapeptide (sulfated) ammonium salt |
|---|---|---|---|---|
| CAS号 | 25126-32-3 | 分子量 | 1143.269 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | N/A | |
| 分子式 | C49H62N10O16S3 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
|
Direct cellular delivery of human proteasomes to delay tau aggregation.
Nat. Commun. 5 , 5633, (2014) The 26S proteasome is the primary machinery that degrades ubiquitin (Ub)-conjugated proteins, including many proteotoxic proteins implicated in neurodegeneraton. It has been suggested that the elevation of proteasomal activity is tolerable to cells and may be... |
|
|
The efficacy and mechanism of apoptosis induction by hypericin-mediated sonodynamic therapy in THP-1 macrophages.
Int. J. Nanomedicine 10 , 821-38, (2015) To investigate the sonoactivity of hypericin (HY), together with its sonodynamic effect on THP-1 macrophages and the underlying mechanism.CCK-8 was used to examine cell viability. Confocal laser scanning microscopy was performed to assess the localization of ... |
|
|
Aroclor 1254 inhibits cell viability and induces apoptosis of human A549 lung cancer cells by modulating the intracellular Ca(2+) level and ROS production through the mitochondrial pathway.
J. Environ. Sci. Health. A. Tox. Hazard. Subst. Environ. Eng. 50 , 806-13, (2015) To study the acute toxic effects of PCBs on airway exposure, the cell viability, apoptosis and mitochondrial functions of human lung cancer cell line A549 were measured and compared after Aroclor 1254 exposure for different time. The results showed that Arocl... |
|
|
Identification of the sAPRIL binding peptide and its growth inhibition effects in the colorectal cancer cells.
PLoS ONE 10(3) , e0120564, (2015) A proliferation-inducing ligand (APRIL) is a member of the tumor necrosis factor (TNF) super family. It binds to its specific receptors and is involved in multiple processes during tumorigenesis and tumor cells proliferation. High levels of APRIL expression a... |
|
|
Fluoxetine Decreases the Proliferation and Adipogenic Differentiation of Human Adipose-Derived Stem Cells.
Int. J. Mol. Sci. 16 , 16655-68, (2015) Fluoxetine was originally developed as an antidepressant, but it has also been used to treat obesity. Although the anti-appetite effect of fluoxetine is well-documented, its potential effects on human adipose-derived stem cells (ASCs) or mature adipocytes hav... |
|
|
Effect of Sodium Fluoride on the Proliferation and Gene Differential Expression in Human RPMI8226 Cells.
Biol. Trace Elem. Res. 167 , 11-7, (2015) Although fluoride is known to reduce the incidence of caries, chronic excessive fluoride exposure can impair human health, even resulting in fluorosis. Now the underlying mechanisms of fluoride-induced toxicity are not fully understood. So, we conducted this ... |
|
|
Knock-down of p300 decreases the proliferation and odontogenic differentiation potentiality of HDPCs.
Int. Endod. J. 48 , 976-85, (2015) To investigate the role of p300 in the regulation of proliferation and odontogenic differentiation of human dental pulp cells (HDPCs).The recombinant lentiviral vector pshRNA-copGFP was used to knock-down p300 expression in HDPCs. Protein level of acetylated ... |
|
|
Apoptosis signal-regulating kinase 1 promotes Ochratoxin A-induced renal cytotoxicity.
Sci. Rep. 5 , 8078, (2015) Oxidative stress and apoptosis are involved in Ochratoxin A (OTA)-induced renal cytotoxicity. Apoptosis signal-regulating kinase 1 (ASK1) is a Mitogen-Activated Protein Kinase Kinase Kinase (MAPKKK, MAP3K) family member that plays an important role in oxidati... |
|
|
Neovibsanin B inhibits human malignant brain tumor cell line proliferation and induces apoptosis.
Int. J. Clin. Exp. Med. 8 , 6456-62, (2015) The present study was designed to examine the effect of neovibsanin B on glioma cell viability, apoptosis and on the survival time in mice bearing tumor xenografts. The results demonstrated that neovibsanin B significantly reduced the cell viability of GL261-... |
|
|
microRNA-218 promotes gemcitabine sensitivity in human pancreatic cancer cells by regulating HMGB1 expression.
Chin. J. Cancer Res. 27 , 267-78, (2015) The purpose of this study was to examine the effect of gemcitabine (GEM) on microRNA-218 (miR-218) expression in human pancreatic cancer cells.Quantitative reverse transcription polymerase chain reaction (qRT-PCR) was performed to examine the differences in m... |