恩贝灵； 恩贝酸
恩贝灵； 恩贝酸结构式
|
常用名 | 恩贝灵； 恩贝酸 | 英文名 | Embelin |
|---|---|---|---|---|
| CAS号 | 550-24-3 | 分子量 | 294.386 | |
| 密度 | 1.131 | 沸点 | 431.9±45.0 °C at 760 mmHg | |
| 分子式 | C17H26O4 | 熔点 | 145-146 ºC | |
| MSDS | 中文版 美版 | 闪点 | 229.1±25.2 °C |
|
Preventive effect of embelin from embelia ribes on lipid metabolism and oxidative stress in high-fat diet-induced obesity in rats.
Planta Med. 78(7) , 651-7, (2012) A high-fat diet (HFD) results in hyperlipidemia and an increase in oxidative stress. The purpose of this study was to investigate the preventive effect of embelin against hyperlipidemia and oxidative stress in HFD-induced obesity in rats. Male Wistar rats age... |
|
|
Embelin ameliorates dextran sodium sulfate-induced colitis in mice
Int. Immunopharmacol. 11(6) , 724-31, (2011) Embelin has been used to treat fever, inflammatory diseases, and a variety of gastrointestinal ailments for thousands of years. Although reports indicate that embelin has anti-inflammatory and anti-tumor effects, its effects on ulcerative colitis have not bee... |
|
|
Inhibition of UVB-induced oxidative damage and apoptotic biochemical changes in human lymphocytes by 2,5-dihydroxy-3-undecyl-1,4-benzoquinone (embelin).
Int. J. Radiat. Biol. 88(8) , 575-82, (2012) The present study investigates the inhibition of Ultraviolet B (UVB, 290-320 nm) radiation-induced oxidative damage in peripheral blood human lymphocytes by embelin extracted from Embelia ribes.Embelin was extracted, purified and characterized. Prior to inhib... |
|
|
Embelin induces apoptosis in human glioma cells through inactivating NF-κB.
J. Pharmacol. Sci. 121(3) , 192-9, (2013) Aggressive tumor growth and diffuse tissue invasion are hallmarks of malignant glioma. Embelin is an active compound identified as a novel XIAP inhibitor from the Embelia ribes that exhibits various medicinal effects including anti-inflammatory and anti-cance... |
|
|
Protective effect of embelin from Embelia ribes Burm. against transient global ischemia-induced brain damage in rats.
Neurotox. Res. 20(4) , 379-86, (2011) Embelia ribes is being used in Indian traditional herbal medicine for the treatment of mental disorders and as brain tonic. The present study was designed to investigate the protective effects of embelin from E. ribes on global ischemia/reperfusion-induced br... |
|
|
Synthesis and evaluation of analgesic and anti-inflammatory activities of most active free radical scavenging derivatives of embelin-A structure-activity relationship.
Chem. Pharm. Bull. 59(8) , 913-9, (2011) Antioxidant and related properties of the plant Embelia ribes and embelin are well known. In the present study embelin was condensed with various aromatic substituted primary amines to yield ten new and one reported derivatives along with monomethyl embelin. ... |
|
|
Inhibition of X-linked inhibitor of apoptosis with embelin differentially affects male versus female behavioral outcome following neonatal hypoxia-ischemia in rats.
Dev. Neurosci. 33(6) , 494-504, (2011) Hypoxia-ischemia (HI; concurrent oxygen/blood deficiency) and associated encephalopathy represent a common cause of neurological injury in premature/low-birth-weight infants and term infants with birth complications. Resulting behavioral impairments include c... |
|
|
Antioxidant activity and protection of pancreatic β-cells by embelin in streptozotocin-induced diabetes.
J. Diabetes 4(3) , 248-56, (2012) The aim of the present study was to evaluate the antioxidant potential of embelin in streptozotocin-induced diabetes. Diabetes was induced in rats fasted overnight by the administration of a single dose of streptozotocin, and analyzed for blood, serum, and b... |
|
|
Embelin accelerates cutaneous wound healing in diabetic rats.
J. Asian Nat. Prod. Res. 15(2) , 158-65, (2013) This study reports the effect of embelin (1) on cutaneous wound in streptozotocin (STZ)-induced diabetic rats. The effect was studied using excision, incision, and dead space models. In diabetic rats, topical application of embelin 5% (w/w) ointment showed a ... |
|
|
RP-HPLC-DAD method for the estimation of embelin as marker in Embelia ribes and its polyherbal formulations.
Biomed. Chromatogr. 25(5) , 600-5, (2011) Evidence-based herbal products with assured quality are assuming importance for complementary and alternative medicine. Traditional medicines by and large are not standardized and validated to meet the new requirements. In the present study, marker (embelin)-... |