尿素
尿素结构式
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常用名 | 尿素 | 英文名 | Urea |
|---|---|---|---|---|
| CAS号 | 57-13-6 | 分子量 | 60.055 | |
| 密度 | 1.335 | 沸点 | 332.48°C | |
| 分子式 | CH4N2O | 熔点 | 131-135 ºC | |
| MSDS | 中文版 美版 | 闪点 | 53.7±22.6 °C |
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A new enabling proteomics methodology to investigate membrane associated proteins from parasitic nematodes: case study using ivermectin resistant and ivermectin susceptible isolates of Caenorhabditis elegans and Haemonchus contortus.
Vet. Parasitol. 207(3-4) , 266-75, (2015) The mechanisms involved in anthelmintic resistance (AR) are complex but a greater understanding of AR management is essential for effective and sustainable control of parasitic helminth worms in livestock. Current tests to measure AR are time consuming and ca... |
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Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking.
Autophagy 10(7) , 1241-55, (2014) Glioblastoma is one of the most aggressive human cancers with poor prognosis, and therefore a critical need exists for novel therapeutic strategies for management of glioblastoma patients. Itraconazole, a traditional antifungal drug, has been identified as a ... |
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Synergistic activity of tenofovir and nevirapine combinations released from polycaprolactone matrices for potential enhanced prevention of HIV infection through the vaginal route.
Eur. J. Pharm. Biopharm. 88(2) , 406-14, (2014) Polycaprolactone (PCL) matrices were simultaneously loaded with the antiviral agents, tenofovir (TFV) and nevirapine (NVP), in combination to provide synergistic activity in the prevention of HIV transmission through the vaginal route. TFV and NVP were incorp... |
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Hepatitis E virus (HEV) protease: a chymotrypsin-like enzyme that processes both non-structural (pORF1) and capsid (pORF2) protein.
J. Gen. Virol. 95(Pt 8) , 1689-700, (2014) Hepatitis E virus (HEV), a major cause of acute viral hepatitis across the world, is a non-enveloped, plus-strand RNA virus. Its genome codes three proteins, pORF1 (multifunctional polyprotein), pORF2 (capsid protein) and pORF3 (multi-regulatory protein). pOR... |
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Influence of the lipid membrane environment on structure and activity of the outer membrane protein Ail from Yersinia pestis.
Biochim. Biophys. Acta 1848(2) , 712-20, (2014) The surrounding environment has significant consequences for the structural and functional properties of membrane proteins. While native structure and function can be reconstituted in lipid bilayer membranes, the detergents used for protein solubilization are... |
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Comparison of the antifungal efficacy of terbinafine hydrochloride and ciclopirox olamine containing formulations against the dermatophyte Trichophyton rubrum in an infected nail plate model.
Mol. Pharm. 11(7) , 1991-6, (2014) Onychomycosis is a fungal infection mostly induced by dermatophytes such as Trichophyton rubrum. Due to slow nail growth, the treatment takes 3-9 months depending on the nail size and infected area. Hence, high efficacy of the active ingredient without system... |
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Interaction of Bordetella pertussis filamentous hemagglutinin with human TLR2: identification of the TLR2-binding domain.
APMIS 123(2) , 156-62, (2015) Filamentous hemagglutinin (FHA) is a major adhesion and virulence factor of Bordetella pertussis and also a main component of acellular pertussis vaccines. Interaction of FHA with different receptors on human epithelial and immune cells facilitates entrance a... |
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Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells.
Nat. Commun. 6 , 6240, (2015) Epstein-Barr virus (EBV) is implicated as an aetiological factor in B lymphomas and nasopharyngeal carcinoma. The mechanisms of cell-free EBV infection of nasopharyngeal epithelial cells remain elusive. EBV glycoprotein B (gB) is the critical fusion protein f... |
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Crystals of Na(+)/K(+)-ATPase with bound cisplatin.
Biochem. Pharmacol. 92(3) , 494-8, (2014) Cisplatin is the most widely used chemotherapeutics for cancer treatment, however, its administration is connected to inevitable adverse effects. Previous studies suggested that cisplatin is able to inhibit Na(+)/K(+)-ATPase (NKA), the enzyme responsible for ... |
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Critical role of p38 MAPK in IL-4-induced alternative activation of peritoneal macrophages.
Eur. J. Immunol. 45(1) , 273-86, (2015) Alternative activation of macrophages plays an important role in a range of physiological and pathological processes. This alternative phenotype, also known as M2 macrophages, is induced by type 2 cytokines such as IL-4. The binding of IL-4 to its receptor le... |