倒千里光裂碱
倒千里光裂碱结构式
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常用名 | 倒千里光裂碱 | 英文名 | Retronecine |
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| CAS号 | 480-85-3 | 分子量 | 155.19400 | |
| 密度 | 1.29g/cm3 | 沸点 | 291.3ºC at 760mmHg | |
| 分子式 | C8H13NO2 | 熔点 | 119-120° | |
| MSDS | 中文版 美版 | 闪点 | 161.4ºC |
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Diversity of pyrrolizidine alkaloids in native and invasive Senecio pterophorus (Asteraceae): implications for toxicity.
Phytochemistry 108 , 137-46, (2014) Changes in plant chemical defenses after invasion could have consequences on the invaded ecosystems by modifying the interactions between plants and herbivores and facilitating invasion success. However, no comprehensive biogeographical studies have yet deter... |
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Transfer of [3H]pyrrolizidine alkaloids from Senecio vulgaris L. and metabolites into rat milk and tissues.
Toxicol. Lett. 17(3-4) , 283-8, (1983) [3H]Retronecine and [3H]necic acid-labelled senecionine and seneciphylline were prepared biosynthetically with seedlings of Senecio vulgaris L. using [2,3-3H]putrescine and [4,5-3H]isoleucine, respectively, as precursors. Lactating rats dosed with these diffe... |
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In vivo covalent binding of retronecine-labelled [3H]seneciphylline and [3H]senecionine to DNA of rat liver, lung and kidney.
Chem. Biol. Interact. 54(1) , 57-69, (1985) Retronecine-labelled [3H]seneciphylline ([3H]SPH) and [3H]senecionine ([3H]SON) of high specific radioactivity (22 and 49 mCi/mmol, respectively) were prepared biosynthetically with seedlings of Senecio vulgaris L. using [2,3-3H]putrescine as precursor. [2,3-... |
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A competitive enzyme-linked immunosorbent assay (ELISA) to detect retronecine and monocrotaline in vitro.
Toxicon 27(9) , 1059-64, (1989) Antibodies to the nonesterified pyrrolizidine nucleus, retronecine (155 mol.wt), were produced in rabbits and detected using an avidin-biotin antibody ELISA. A competitive ELISA for the detection of retronecine and the cyclic diester monocrotaline was also de... |
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Metabolic activation of retronecine and retronecine N-oxide - formation of DHP-derived DNA adducts.
Toxicol. Ind. Health 24(3) , 181-8, (2008) We have previously reported that metabolism of a series of pyrrolizidine alkaloids in vitro and in vivo generated a set of (+/-)6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-derived DNA adducts. It has also been shown that the levels of the DHP-d... |
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Dehydropyrrolizidine alkaloids in two Cryptantha species: including two new open chain diesters one of which is amphoteric.
Phytochem. Anal. 24(3) , 201-12, (2013) A livestock poisoning outbreak near Kingman, Arizona, USA, potentially linked to dehydropyrrolizidine alkaloids, prompted an evaluation of some local plants for the presence of these hepatotoxic alkaloids.To qualitatively and quantitatively examine two specie... |
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Are insect-synthesized retronecine esters (creatonotines) the precursors of the male courtship pheromone in the arctiid moth Estigmene acrea?
J. Chem. Ecol. 29(11) , 2603-8, (2003) The pyrrolizidine alkaloid (PA) profiles were determined for adults of the polyphagous arctiid Estigmene acrea, which as larvae had fed on artificial diet supplemented with Crotalaria-pumila powder with known concentrations of PAs. The larvae always had a fre... |
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¹H NMR study of monocrotaline and its metabolites in human blood.
Food Chem. Toxicol. 49(11) , 2793-9, (2011) Monocrotaline (MCT) is a naturally occurring hepatotoxic pyrrolizidine alkaloid found in plants. This investigation is aimed at furthering the understanding of the role of blood in mediating the transport of MCT and its reactive metabolites in humans. Reactio... |
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Major components in the hairpencil secretion of a butterfly, Euploea mulciber (Lepidoptera, Danaidae): their origins and male behavioral responses to pyrrolizidine alkaloids.
J. Insect Physiol. 52(10) , 1043-53, (2006) Two compounds, 9,10-epoxytetrahydroedulan (ET) and viridiflorine beta-lactone (VL), were identified as major components from the hairpencils of field-caught males of a danaid butterfly, Euploea mulciber. By contrast, laboratory-reared males entirely lacked VL... |
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Morphogenetic effects of alkaloidal metabolites on the development of the coremata in the salt marsh moth, Estigmene acrea (Dru.) (Lepidoptera: Arctiidae).
Arch. Insect Biochem. Physiol. 66(4) , 183-9, (2007) Pyrrolizidine alkaloids (PAs) play a fundamental role in the sexual biology of the salt marsh moth Estigmene acrea. They are precursors for the male courtship pheromone hydroxydanaidal and they stimulate the growth and development of male pheromone-disseminat... |