盐酸萘替芬

盐酸萘替芬结构式
盐酸萘替芬结构式
品牌特惠专场
常用名 盐酸萘替芬 英文名 Naftifine hydrochloride
CAS号 65473-14-5 分子量 323.859
密度 N/A 沸点 440.1ºC at 760 mmHg
分子式 C21H22ClN 熔点 172-175ºC
MSDS 中文版 美版 闪点 194.4ºC

DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.

Nucleic Acids Res. 39 , D1035-41., (2011)

DrugBank (http://www.drugbank.ca) is a richly annotated database of drug and drug target information. It contains extensive data on the nomenclature, ontology, chemistry, structure, function, action, pharmacology, pharmacokinetics, metabolism and pharmaceutic...

Allergic contact dermatitis from naftifine in a child without cross-reaction to terbinafine.

J. Eur. Acad. Dermatol. Venereol. 11(1) , 72-3, (1998)

Allergic contact dermatitis from naftifine has been scarcely described in the English literature, all of them in adults. We report a case of a 12-year-old girl who developed an acute eczema on her neck after application of a naftifine cream. This fact was con...

RIPK3-mediated necroptosis regulates cardiac allograft rejection.

Journal. of. Drugs in. Dermatology. 10(11) , 1282-8, (2011)

Cell death results in tissue damage and ultimately donor graft rejection and can occur as an active molecular process through apoptotic, necrotic and newly identified receptor interacting protein 1 and 3 kinase (RIPK1/3)-mediated necroptotic pathways. Necropt...

A double-blind, randomized, vehicle-controlled study evaluating the efficacy and safety of naftifine 2% cream in tinea cruris.

Journal. of. Drugs in. Dermatology. 10(10) , 1142-7, (2011)

Naftifine HCl 2% cream (NAFT-2%) is a topical allylamine antifungal preparation under development in the U.S. The objective of this randomized, double-blind, vehicle-controlled study was to evaluate the efficacy and safety of a two-week course of once-daily N...

Development of naftifine hydrochloride alcohol-free niosome gel.

Drug Dev. Ind. Pharm. 35(5) , 631-7, (2009)

Marketed topical gels of the antifungal drug naftifine hydrochloride contain 50% alcohol as cosolvent. Repeated exposure to alcohol could be detrimental to skin. The aim of this study is to develop an alcohol-free niosome gel containing 1% naftifine hydrochlo...

Seborrhoeic dermatitis-like tinea faciei in an infant.

Mycoses 50(6) , 525-6, (2007)

The patient we present herein is a 6-month-old infant who had erythema and scaling on the central part of the face for 4 months. Both the abundant scaling and the localisation, but also the low age of this infant led to suspect seborrhoeic dermatitis. Direct ...

[Treatment of interdigital tinea pedis].

Dtsch. Med. Wochenschr. 128(36) , 1819-24, (2003)

Local antimycotic therapy of interdigital tinea pedis is widely accepted and efficacious. In Germany at present, the azoles and allylamines--part from the hydroxypyridone derivative ciclopiroxolamine--are the pharmacological agents applied most often. This st...

An open-label pilot study of naftifine 1% gel in the treatment of seborrheic dermatitis of the scalp.

Journal. of. Drugs in. Dermatology. 11(4) , 514-8, (2012)

Topical antifungal treatment is a mainstay of therapy for Seborrehic Dermatitis (SD). Although the amidazole and ciclopyridine antifungals have been extensively studied, few clinical efficacy data are available for topical allylamine therapy in SD. The object...

Comparative study of the in vitro antifungal activity of bifonazole, naftifine and sertaconazole against yeasts.

J. Chemother. 11(3) , 187-90, (1999)

The in vitro activity of three antifungal agents was tested and compared against 151 yeast strains, including ten Candida species, Cryptococcus neoformans, Rhodotorula rubra, and Trichosporon cutaneum. Minimum inhibitory concentrations (MICs) were determined ...

Naftifine, a topical allylamine.

Journal. of. Drugs in. Dermatology. 9(7) , 750, (2010)