聚脱氧腺苷酸.聚胸苷酸 钠盐
聚脱氧腺苷酸.聚胸苷酸 钠盐结构式
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常用名 | 聚脱氧腺苷酸.聚胸苷酸 钠盐 | 英文名 | POLYDEOXYADENYLIC ACID-POLYTHYMIDYLIC ACID SODIUM SALT |
|---|---|---|---|---|
| CAS号 | 86834-22-2 | 分子量 | 653.43000 | |
| 密度 | N/A | 沸点 | 753.5ºC at 760 mmHg | |
| 分子式 | C20H29N7O14P2 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | 409.5ºC |
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Homopolymer tract length dependent enrichments in functional regions of 27 eukaryotes and their novel dependence on the organism DNA (G+C)% composition.
BMC Genomics 5 , 95, (2004) DNA homopolymer tracts, poly(dA).poly(dT) and poly(dG).poly(dC), are the simplest of simple sequence repeats. Homopolymer tracts have been systematically examined in the coding, intron and flanking regions of a limited number of eukaryotes. As the number of D... |
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Energetics of binding the mammalian high mobility group protein HMGA2 to poly(dA-dT)2 and poly(dA)-poly(dT).
J. Mol. Biol. 352(3) , 629-45, (2005) The mammalian high mobility group protein A2 (HMGA2) is a chromosomal architectural transcription factor involved in oncogenesis and cell transformation. It has three "AT-hook" DNA binding domains, which specifically bind to the minor groove of AT DNAs. The i... |
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Poly(dA).poly(dT) forms very stable nucleosomes at higher temperatures.
J. Mol. Biol. 245(5) , 559-67, (1995) The synthetic polymer poly(dA).poly(dT) was long thought to be refractory to nucleosome formation. Several years ago our laboratory demonstrated that the polymer could be mixed with authentic nucleosomes in a low-salt exchange procedure to form a nucleoprotei... |
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Investigation of DNA binding modes for a symmetrical cyanine dye trication: effect of DNA sequence and structure.
J. Biomol. Struct. Dyn. 18(6) , 844-56, (2001) The DNA binding behavior of a tricationic cyanine dye (DiSC3+(5)) was studied using the [Poly(dA-dT)]2, [Poly(dI-dC)]2 and Poly(dA) x Poly(dT) duplex sequences and the Poly(dA) x 2Poly(dT) triplex. Optical spectroscopy and viscometry results indicate that the... |
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[Hydration and stability of the double helical complex poly(dA)-poly(dT)].
Biofizika 39(4) , 628-36, (1994) IR-spectrometry and thermopiezogravimetry are used to study the structure formation and the water environment of the double-helix Na-poly(dA)-poly(dT) complex in films in the 0-100% interval of the relative humidity (RH). It has been found that three differen... |
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Dispersion of meso-tetrakis(N-methylpyridinium-4-yl)porphyrin on [d(A-T)n]2 oligonucleotides.
Biochim. Biophys. Acta 1726(3) , 287-92, (2005) The binding modes of the free-base meso-tetrakis(N-methylpyridinium-4-yl)porphyrin (TMPyP) complexed with [d(AT)n]2 oligonucleotides (where n=3-8, corresponding to 6 to 16 AT base pairs) were studied by circular dichroism (CD). When associated with the shorte... |
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A role for poly(dA)poly(dT) tracts in directing activity of the Plasmodium falciparum calmodulin gene promoter.
Mol. Biochem. Parasitol. 141(2) , 179-89, (2005) Expression of the Plasmodium falciparum calmodulin gene (pfcam) is developmentally regulated throughout the blood-stage cycle. The promoter lies within approximately 1 kb of intergenic sequence that separates the pfcam open reading frame (ORF) from an upstrea... |
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DNA binding properties of novel distamycin analogs that lack the leading amide unit at the N-terminus.
Biochem. Biophys. Res. Commun. 267(1) , 139-44, (2000) First examples of distamycin (Dst) analogs which lack hydrogen bond donor or acceptor groups at the N-terminus have been synthesized. The first molecule of this series, which is a bispyrrole peptide, did not exhibit any detectable binding with double-stranded... |
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Titration of poly(dA-dT) . poly(dA-dT) in solution at variable NaCl concentration.
Biopolymers 75(2) , 118-27, (2004) CD and uv absorption data showed that high molecular weight poly(dA-dT) . poly(dA-dT), at 298 K, undergoes an acid-induced transition from B-double helix to random coil in NaCl solutions of different concentrations, ranging from 0.005 to 0.600M. Similarly, ti... |
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Unusual DNA binding exhibited by synthetic distamycin analogues lacking the N-terminal amide unit under high salt conditions.
J. Biomol. Struct. Dyn. 18(6) , 858-71, (2001) The binding of three analogues of the minor-groove binding antiviral antibiotic distamycin (Dst) with double-stranded (ds)-DNA were monitored using ds-DNA melting temperature (Tm) measurements, ethidium bromide (EtBr) displacement assay, footprinting analysis... |