吐温20结构式
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常用名 | 吐温20 | 英文名 | Tween 20 |
|---|---|---|---|---|
| CAS号 | 9005-64-5 | 分子量 | 604.813 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 695.8±55.0 °C at 760 mmHg | |
| 分子式 | C26H50O10 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 207.1±25.0 °C |
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Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors.
Oncotarget 6 , 8539-51, (2015) Colorectal cancer is a major health problem and the second cause of cancer related death in western countries. Signaling pathways that control tissue homeostasis are often deregulated during tumorigenesis and contribute to tumor development. Studies in mouse ... |
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Pharmacogenomic and clinical data link non-pharmacokinetic metabolic dysregulation to drug side effect pathogenesis.
Nat. Commun. 6 , 7101, (2015) Drug side effects cause a significant clinical and economic burden. However, mechanisms of drug action underlying side effect pathogenesis remain largely unknown. Here, we integrate pharmacogenomic and clinical data with a human metabolic network and find tha... |
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Interleukin-10 conjugated electrospun polycaprolactone (PCL) nanofibre scaffolds for promoting alternatively activated (M2) macrophages around the peripheral nerve in vivo.
J. Immunol. Methods 420 , 38-49, (2015) Macrophages play a key role in tissue regeneration following peripheral nerve injury by preparing the surrounding parenchyma for regeneration, however, they can be damaging if the response is excessive. Interleukin 10 (IL-10) is a cytokine that promotes macro... |
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Immunophoretic rapid diagnostic tests as a source of immunoglobulins for estimating malaria sero-prevalence and transmission intensity.
Malaria Journal 8 , 168, (2009) Sero-epidemiological methods are being developed as a tool for rapid assessment of malaria transmission intensity. Simple blood collection methods for use in field settings will make this more feasible. This paper describes validation of such a method, by ana... |
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Expression of RHOGTPase regulators in human myometrium.
Reprod. Biol. Endocrinol. 6 , 1, (2008) RHOGTPases play a significant role in modulating myometrial contractility in uterine smooth muscle. They are regulated by at least three families of proteins, RHO guanine nucleotide exchange factors (RHOGEFs), RHOGTPase-activating proteins (RHOGAPs) and RHO g... |
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RAB24 facilitates clearance of autophagic compartments during basal conditions.
Autophagy 11 , 1833-48, (2015) RAB24 belongs to a family of small GTPases and has been implicated to function in autophagy. Here we confirm the intracellular localization of RAB24 to autophagic vacuoles with immuno electron microscopy and cell fractionation, and show that prenylation and g... |
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Stromagenesis during tumorigenesis: characterization of tumor-associated fibroblasts and stroma-derived 3D matrices.
Methods Mol. Biol. 522 , 275-305, (2009) It is increasingly recognized that interactions between cancer cells and their surrounding stroma are critical for promoting the growth and invasiveness of tumors. For example, cancer cells alter the topography and molecular composition of stromal extracellul... |
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Combination of immortalization and inducible death strategies to generate a human mesenchymal stromal cell line with controlled survival.
Stem Cell Res. 12(2) , 584-98, (2014) The hTERT-immortalization of human bone marrow-derived Mesenchymal Stromal Cells (hMSCs) was proposed to address availability/standardization issues for experimental or clinical studies, but raised concerns due to possible uncontrolled growth or malignant cel... |
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Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor h-binding protein.
Infect. Immun. 76(9) , 4232-40, (2008) No broadly protective vaccine is available for the prevention of group B meningococcal disease. One promising candidate is factor H-binding protein (fHbp), which is present in all strains but often sparsely expressed. We prepared seven murine immunoglobulin G... |
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A protocol for the production of recombinant spider silk-like proteins for artificial fiber spinning.
Nat. Protoc. 4 , 341-55, (2009) The extreme strength and elasticity of spider silks originate from the modular nature of their repetitive proteins. To exploit such materials and mimic spider silks, comprehensive strategies to produce and spin recombinant fibrous proteins are necessary. This... |