对甲氧基肉桂酸辛酯
对甲氧基肉桂酸辛酯结构式
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常用名 | 对甲氧基肉桂酸辛酯 | 英文名 | Octyl 4-methoxycinnamate |
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| CAS号 | 5466-77-3 | 分子量 | 290.397 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 405.3±20.0 °C at 760 mmHg | |
| 分子式 | C18H26O3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 171.6±16.4 °C |
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Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
J. Sci. Ind. Res. 65(10) , 808, (2006) Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be tra... |
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Developing structure-activity relationships for the prediction of hepatotoxicity.
Chem. Res. Toxicol. 23 , 1215-22, (2010) Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification o... |
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A predictive ligand-based Bayesian model for human drug-induced liver injury.
Drug Metab. Dispos. 38 , 2302-8, (2010) Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predictive in vivo, in vitro, and in silico models to identify comp... |
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Atmospheric pressure gas chromatography-time-of-flight-mass spectrometry (APGC-ToF-MS) for the determination of regulated and emerging contaminants in aqueous samples after stir bar sorptive extraction (SBSE).
Anal. Chim. Acta 851 , 1-13, (2014) This work presents the development, optimization and validation of a multi-residue method for the simultaneous determination of 102 contaminants, including fragrances, UV filters, repellents, endocrine disruptors, biocides, polycyclic aromatic hydrocarbons (P... |
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Growth of cedar-like Au nanoparticles coating on an etched stainless steel wire and its application for selective solid-phase microextraction.
Anal. Chim. Acta 876 , 55-62, (2015) A novel cedar-like Au nanoparticles (AuNPs) coating was fabricated on an etched stainless steel (SS) wire by direct chemical deposition and used as an efficient and unbreakable solid phase microextraction (SPME) fiber. The etched SS wire offers a rough surfac... |
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Fabrication and application of zinc-zinc oxide nanosheets coating on an etched stainless steel wire as a selective solid-phase microextraction fiber.
J. Chromatogr. A. 1384 , 28-36, (2015) A novel zinc-zinc oxide (Zn-ZnO) nanosheets coating was directly fabricated on an etched stainless steel wire substrate as solid-phase microextraction (SPME) fiber via previous electrodeposition of robust Zn coating. The scanning electron micrograph of the Zn... |
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Determination of ultraviolet filters in bathing waters by stir bar sorptive-dispersive microextraction coupled to thermal desorption-gas chromatography-mass spectrometry.
Talanta 147 , 246-52, (2015) In this work, a new approach that combines the advantages of stir bar sorptive extraction (SBSE) and dispersive solid phase extraction (DSPE), i.e. stir bar sorptive-dispersive microextraction (SBSDµE), is employed as enrichment and clean-up technique for the... |
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Co-occurrence of musk fragrances and UV-filters in seafood and macroalgae collected in European hotspots.
Environ. Res. 143 , 65-71, (2015) In the last decades, awareness regarding personal care products (PCP), i.e. synthetic organic chemicals frequently used in cosmetic and hygienic products, has become a forward-looking issue, due to their persistency in the environment and their potential mult... |
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Supervised exercise, stent revascularization, or medical therapy for claudication due to aortoiliac peripheral artery disease: the CLEVER study.
J. Am. Coll. Cardiol. 65(10) , 999-1009, (2015) Treatment for claudication that is due to aortoiliac peripheral artery disease (PAD) often relies on stent revascularization (ST). However, supervised exercise (SE) is known to provide comparable short-term (6-month) improvements in functional status and qual... |
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Octyl methoxycinnamate modulates gene expression and prevents cyclobutane pyrimidine dimer formation but not oxidative DNA damage in UV-exposed human cell lines.
Toxicol. Sci. 114(2) , 272-284, (2010) Octyl methoxycinnamate (OMC) is one of the most widely used sunscreen ingredients. To analyze biological effects of OMC, an in vitro approach was used implying ultraviolet (UV) exposure of two human cell lines, a primary skin fibroblast (GM00498) and a breast... |