层粘连蛋白(929-933)
层粘连蛋白(929-933)结构式
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常用名 | 层粘连蛋白(929-933) | 英文名 | H-Tyr-Ile-Gly-Ser-Arg-OH trifluoroacetate salt |
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| CAS号 | 110590-64-2 | 分子量 | 594.66000 | |
| 密度 | 1.44 g/cm3 | 沸点 | N/A | |
| 分子式 | C26H42N8O8 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A |
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Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices.
Integr. Biol. (Camb.) 3(3) , 185-96, (2011) Extracellular matrices (ECMs) are complex materials, containing at least dozens of different macromolecules that are assembled together, thus complicating their optimization towards applications in 3D cell culture or tissue engineering. The natural complexity... |
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Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor.
FASEB J. 20(7) , 906-15, (2006) It has been reported that extracellular matrix (ECM) molecules regulate monocyte activation by binding with a 67 kDa nonintegrin laminin receptor (LR). As microgliosis is a pivotal factor in propelling the progress of chronic neurodegeneration in the brain, w... |
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Malignancy-related 67kDa laminin receptor in adenoid cystic carcinoma. Effect on migration and beta-catenin expression.
Oral Oncol. 43(10) , 987-98, (2007) Adenoid cystic carcinoma is a malignant salivary gland neoplasm with recurrence and metastasis. We studied the expression of a malignancy-related non-integrin laminin receptor, the 67LR, in this neoplasm. Immunohistochemistry showed 67LR in adenoid cystic car... |
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Effects of a laminin peptide (YIGSR) immobilized on crab-tendon chitosan tubes on nerve regeneration.
J. Biomed. Mater. Res. B. Appl. Biomater. 73(2) , 375-82, (2005) Thiolated and nonthiolated hydroxyapatite-coated crab-tendon chitosan (t-chitosan/HAp-SH and t-chitosan/HAp, respectively) tubes, both alone and conjugated with CDPGYIGSR (YIGSR) peptide, were compared, in order to determine their biocompatibility and efficac... |
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Laminin-111-derived peptides and cancer.
Cell Adh. Migr. 7(1) , 150-256, (2013) Laminin-111 is a large trimeric basement membrane glycoprotein with many active sites. In particular, four peptides active in tumor malignancy studies have been identified in laminin-111 using a systematic peptide screening method followed by various assays. ... |
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Conformationally constrained mimetics of laminin peptide YIGSR as precursors for antimetastatic disintegrins.
J. Med. Chem. 52(24) , 7966-9, (2009) Conformationally constrained mimetics of the laminin cell-adhesion site, YIGSR, are described. The site is the natural antagonist of the integrin-associated laminin receptor 1 (LAMR1) known to mediate metastatic tumor adhesion. The attachment of selected meta... |
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Liposomes modified with YIGSR peptide for tumor targeting.
J. Drug Target. 18(5) , 373-80, (2010) YIGSR peptide anchored sterically stabilized liposomes (YIGSR-SL) were investigated for selective and preferential presentation of carrier contents at angiogenic endothelial cells overexpressing laminin receptors on and around tumor tissue and thus for assess... |
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Enhancement of gene transfer using YIGSR analog of Tat-derived peptide.
Biopolymers 89(1) , 62-71, (2008) Cell penetrating peptide based gene carriers are notably known for low level of gene transfer. To remedy this, as laminin receptor (LR) has been previously linked to tumor metastasis, the LR-binding domain (YIGSR) as well as a scrambled sequence (SGIYR) were ... |
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Laminin peptide YIGSR induces collagen synthesis in Hs27 human dermal fibroblasts.
Biochem. Biophys. Res. Commun. 428(3) , 416-21, (2012) The dermal ECM is synthesized from fibroblasts and is primarily compromised of fibrillar collagen and elastic fibers, which support the mechanical strength and resiliency of skin, respectively. Laminin, a major glycoprotein located in the basement membrane, p... |
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Laminin peptide YIGSR and its receptor regulate sensory axonal response to the chemoattractive guidance cue in the chick embryo.
J. Neurosci. Res. 87(2) , 353-9, (2009) During early development, centrally projecting dorsal root ganglion (DRG) neurons extend their axons toward the dorsal spinal cord. We previously reported the involvement of dorsal spinal cord-derived chemoattraction in this projection (Masuda et al. [ 2007] ... |