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PEPA

PEPA结构式
PEPA结构式
品牌特惠专场
常用名 PEPA 英文名 PEPA
CAS号 141286-78-4 分子量 402.43600
密度 N/A 沸点 N/A
分子式 C16H16F2N2O4S2 熔点 N/A
MSDS 中文版 美版 闪点 N/A

Positive modulation of AMPA receptors prevents downregulation of GluR2 expression and activates the Lyn-ERK1/2-CREB signaling in rat brain ischemia.

Psychopharmacology 20 , 65-77, (2010)

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) are responsible for excitotoxicity induced by ischemic injury in hippocampal CA1 neurons, whereas the molecular mechanisms responsible for their neurotrophic activities are much less ...

Activation of AMPA receptor in the infralimbic cortex facilitates extinction and attenuates the heroin-seeking behavior in rats.

Neurosci. Lett. 612 , 126-31, (2016)

Infralimbic cortex (IL) is proposed to suppress cocaine seeking after extinction, but whether the IL regulates the extinction and reinstatement of heroin-seeking behavior is unknown. To address this issue, the male SD rats were trained to self-administer hero...

The rostromedial tegmental nucleus modulates behavioral inhibition following cocaine self-administration in rats.

Neuropsychopharmacology 40(4) , 861-73, (2015)

Recent findings suggest that the mesolimbic dopamine neurons, known to promote cocaine-seeking behavior, are strongly inhibited by a newly characterized region of the midbrain known as the rostromedial tegmental nucleus (RMTg). The RMTg appears to be involved...