L-Histidine Decarboxylase
L-Histidine Decarboxylase结构式
|
常用名 | L-Histidine Decarboxylase | 英文名 | L-Histidine Decarboxylase |
|---|---|---|---|---|
| CAS号 | 9024-61-7 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | N/A | 熔点 | N/A | |
| MSDS | N/A | 闪点 | N/A |
|
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res. 14 , 2121-7, (2004) The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for every human and mouse gene. The project initially used a r... |
|
|
Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice.
Neuron 81(1) , 77-90, (2014) Tourette syndrome (TS) is characterized by tics, sensorimotor gating deficiencies, and abnormalities of cortico-basal ganglia circuits. A mutation in histidine decarboxylase (Hdc), the key enzyme for the biosynthesis of histamine (HA), has been implicated as ... |
|
|
Prevention of topical surfactant-induced itch-related responses by chlorogenic acid through the inhibition of increased histamine production in the epidermis.
J. Pharmacol. Sci. 121(3) , 242-5, (2013) Effects of chlorogenic acid on surfactant-induced itching were studied in mice. Topical application of sodium laurate increased hind-paw scratching, an itch-related response, 2 h after application, which was inhibited by topical post-treatment with chlorogeni... |
|
|
The consensus coding sequences of human breast and colorectal cancers.
Science 314(5797) , 268-74, (2006) The elucidation of the human genome sequence has made it possible to identify genetic alterations in cancers in unprecedented detail. To begin a systematic analysis of such alterations, we determined the sequence of well-annotated human protein-coding genes i... |
|
|
Two-step differentiation of mast cells from induced pluripotent stem cells.
Stem Cells Dev. 22(5) , 726-34, (2013) Mast cells play important roles in the pathogenesis of allergic diseases. They are generally classified into 2 phenotypically distinct populations: connective tissue-type mast cells (CTMCs) and mucosal-type mast cells (MMCs). The number of mast cells that can... |
|
|
GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep-wake switch or propofol-induced loss of consciousness.
J. Neurosci. 32(38) , 13062-75, (2012) The activity of histaminergic neurons in the tuberomammillary nucleus (TMN) of the hypothalamus correlates with an animal's behavioral state and maintains arousal. We examined how GABAergic inputs onto histaminergic neurons regulate this behavior. A prominent... |
|
|
Histamine synthesis is required for granule maturation in murine mast cells.
Eur. J. Immunol. 44(1) , 204-14, (2014) Mast cells are the major sources of histamine, which is released in response to immunological stimulations. The synthesis of histamine is catalyzed by histidine decarboxylase (HDC). Previous studies have shown that Hdc(-/-) mast cells exhibit aberrant granule... |
|
|
Protective effect of carnosine on subcortical ischemic vascular dementia in mice.
CNS Neurosci. Ther. 18(9) , 745-53, (2012) Recently, we found carnosine protects against N-Methyl-D-Aspartate (NMDA) induced excitotoxicity through a histaminergic pathway. The aim of this study was to determine whether the carnosine-histidine-histamine pathway also played a protective role in subcort... |
|
|
Pathophysiologic role of histamine: evidence clarified by histidine decarboxylase gene knockout mice.
Int. Arch. Allergy Immunol. 158 Suppl 1 , 2-6, (2012) The role of histamine in various murine disease models has been clarified using histidine decarboxylase gene knockout mice. The mice were generated using conventional gene-targeting methods. Studies, including ours, using knockout mice have shown that the act... |
|
|
Histamine: an undercover agent in multiple rare diseases?
J. Cell. Mol. Med. 16(9) , 1947-60, (2012) Histamine is a biogenic amine performing pleiotropic effects in humans, involving tasks within the immune and neuroendocrine systems, neurotransmission, gastric secretion, cell life and death, and development. It is the product of the histidine decarboxylase ... |