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NS3694

NS3694结构式
NS3694结构式
品牌特惠专场
常用名 NS3694 英文名 NS3694
CAS号 426834-38-0 分子量 358.70000
密度 1.574g/cm3 沸点 378.448ºC at 760 mmHg
分子式 C15H10ClF3N2O3 熔点 N/A
MSDS 中文版 美版 闪点 182.679ºC

The novel HDAC inhibitor AR-42-induced anti-colon cancer cell activity is associated with ceramide production.

Biochem. Biophys. Res. Commun. 463 , 545-50, (2015)

In the current study, we investigated the potential activity of AR-42, a novel histone deacetylase (HDAC) inhibitor, against colon cancer cells. Our in vitro results showed that AR-42 induced ceramide production, exerted potent anti-proliferative and pro-apop...

An epistatic effect of apaf-1 and caspase-9 on chlamydial infection.

Apoptosis 20 , 1271-80, (2015)

Chlamydia is an obligate intracellular bacterial pathogen that replicates solely within a membrane-bound vacuole termed an inclusion. Chlamydia seems to perturb multiple cellular processes of the host, such as, rearrangement of the membrane trafficking system...

Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide.

PLoS Pathog. 11 , e1004853, (2015)

Most bacterial infections induce the activation of polymorphonuclear neutrophils (PMNs), enhance their microbicidal function, and promote the survival of these leukocytes for protracted periods of time. Brucella abortus is a stealthy pathogen that evades inna...