甲状旁腺激素(1-34)(牛)
甲状旁腺激素(1-34)(牛)结构式
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常用名 | 甲状旁腺激素(1-34)(牛) | 英文名 | pTH (1-34) (bovine) |
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| CAS号 | 12583-68-5 | 分子量 | 4108.71 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C183H288N54O50S2 | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
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Thyroid hormones enhance the biomechanical functionality of scaffold-free neocartilage.
Arthritis. Res. Ther. 17 , 28, (2015) The aim of this study was to investigate the effects of thyroid hormones tri-iodothyronine (T3), thyroxine (T4), and parathyroid hormone (PTH) from the parathyroid glands, known to regulate the developing limb and growth plate, on articular cartilage tissue r... |
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Identification of a novel parathyroid hormone-responsive gene in human osteoblastic cells.
Bone 24(4) , 305-13, (1999) Parathyroid hormone (PTH) is a potent stimulator of osteoblastic cell function in vitro and bone resorption and formation in vivo; however, the details of the molecular mechanism(s) responsible for PTH action and the regulation of gene expression in response ... |
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Functional properties of a synthetic chicken parathyroid hormone-related protein 1-36 fragment.
J. Bone Miner Res. 9(7) , 1041-6, (1994) The biologic activities of human parathyroid hormone-related protein [hPTHrP(1-34] and bovine PTH [bPTH(1-34)] are remarkably similar despite marked sequence divergence in their primary binding domain, residues 25-34. Chicken PTHrP (cPTHrP) is identical to hP... |
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Comparison of the effects of various lengths of synthetic human parathyroid hormone-related peptide (hPTHrP) of malignancy on bone resorption and formation in organ culture.
Bone 14(5) , 717-20, (1993) Parathyroid hormone-related peptide (PTHrP) has been shown to be the pathogenic agent in humoral hypercalcemia of malignancy (HHM), but the molecular forms that are secreted have not been fully characterized. PTHrP 1-34 has effects similar to parathyroid horm... |
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Anomalous effects of hormone fragments on the measurement of parathyroid hormone by radioimmunoassay.
Methods Find. Exp. Clin. Pharmacol. 18(2) , 87-99, (1996) One of the basic assumptions underlying the use of radioimmunoassay and other competitive protein-binding assays is the homogeneity of the antigen or ligand. This assumption is not valid for the measurement of parathormone (PTH) because of the presence of fra... |
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Functional evidence for an intramolecular side chain interaction between residues 6 and 10 of receptor-bound parathyroid hormone analogues.
Biochemistry 42(8) , 2282-90, (2003) The N-terminal domain of PTH(1-34) is critical for PTH-1 receptor (P1R) activation and has been postulated to be alpha-helical when bound to the receptor. We investigated the possibility that the side chains of residues 6 (Gln) and 10 (Gln or Asn) of PTH anal... |
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Residue 19 of the parathyroid hormone (PTH) modulates ligand interaction with the juxtamembrane region of the PTH-1 receptor.
Biochemistry 41(44) , 13224-33, (2002) Recent data suggest that the binding of parathyroid hormone (PTH)-(1-34) to the PTH-1 receptor (P1R) involves a high-affinity interaction between the C-terminal (15-34) domain of the ligand and the amino-terminal extracellular (N) domain of the receptor and a... |
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Parathyroid hormone transport effects and hormonal processing in primary cultured rat proximal tubular cells.
Biochem. J. 293 ( Pt 2) , 377-80, (1993) The development of satisfactory cell culture models for the study of parathyroid hormone (PTH)-induced inhibition of Pi transport has proven difficult. Using subcellular fractionation techniques we investigated the response of primary cultures of rat proximal... |
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PTH stimulated growth and decreased Col-X deposition are phosphotidylinositol-3,4,5 triphosphate kinase and mitogen activating protein kinase dependent in avian sterna.
Anat. Rec. (Hoboken.) 293(2) , 225-34, (2010) Type X collagen (Col-X) deposition is a marker of terminal differentiation during chondrogenesis, in addition to appositional growth and apoptosis. The parathyroid hormone/parathyroid hormone related peptide (PTH/PTHrP) receptor, or PPR, is a G-Protein couple... |
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Inhibition of parathyroid hormone-stimulated resorption in cultured fetal rat long bones by the main metabolites of ipriflavone.
Calcif. Tissue Int. 58(6) , 419-22, (1996) Ipriflavone is an isoflavone derivative used in the prevention and treatment of postmenopausal and senile osteoporosis in humans. To assess the potential contribution of the main in vivo ipriflavone metabolites (M1, M2, M3, and M5) on the pharmacological prop... |