磷酸二酯酶II
磷酸二酯酶II结构式
|
常用名 | 磷酸二酯酶II | 英文名 | Phosphodiesterase II |
|---|---|---|---|---|
| CAS号 | 9068-54-6 | 分子量 | N/A | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | N/A | 熔点 | N/A | |
| MSDS | 美版 | 闪点 | N/A |
|
PdeH, a high-affinity cAMP phosphodiesterase, is a key regulator of asexual and pathogenic differentiation in Magnaporthe oryzae.
PLoS Pathog. 6(5) , e1000897, (2010) Cyclic AMP-dependent pathways mediate the communication between external stimuli and the intracellular signaling machinery, thereby influencing important aspects of cellular growth, morphogenesis and differentiation. Crucial to proper function and robustness ... |
|
|
The role of cyclic nucleotide phosphodiesterases in the regulation of adipocyte lipolysis.
J. Lipid Res. 46(3) , 494-503, (2005) This study assessed the effects of selective inhibitors of 3',5'-cyclic nucleotide phosphodiesterases (PDEs) on adipocyte lipolysis. IC224, a selective inhibitor of type 1 phosphodiesterase (PDE1), suppressed lipolysis in murine 3T3-L1 adipocytes (69.6 +/- 5.... |
|
|
Identification of bifunctional GA and AG intrastrand crosslinks formed between cisplatin and DNA.
J. Inorg. Biochem. 99(2) , 552-9, (2005) A combination of enzymatic digestion and electrospray ionisation mass spectrometry (ESI-MS) was used to characterise bifunctional adducts in which cisplatin is bound to GA base sequences in 8mer and 16mer oligonucleotides that do not contain other, higher aff... |
|
|
Single-nucleotide polymorphisms: analysis by mass spectrometry.
Nat. Protoc. 1(4) , 1761-71, (2006) Matrix-assisted laser desorption-ionization (MALDI) mass spectrometry has evolved as a powerful method for analyzing nucleic acids. Here we provide protocols for genotyping single-nucleotide polymorphisms (SNPs) by MALDI based on PCR and primer extension to g... |
|
|
Heterogeneous sensory innervation and extensive intrabulbar connections of olfactory necklace glomeruli.
PLoS ONE 4(2) , e4657, (2009) The mammalian nose employs several olfactory subsystems to recognize and transduce diverse chemosensory stimuli. These subsystems differ in their anatomical position within the nasal cavity, their targets in the olfactory forebrain, and the transduction mecha... |
|
|
Sequence confirmation of chemically modified RNAs using exonuclease digestion and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Rapid Commun. Mass Spectrom. 23(21) , 3423-30, (2009) A broadly applicable, robust, and rapid method for complete sequence confirmation of highly modified oligonucleotides containing a mixture of 2'-deoxy, 2'-fluoro, 2'-o-methyl, abasic and ribonucleotides is presented. The passenger (sense) and guide (antisense... |
|
|
Defining amino acid residues involved in DNA-protein interactions and revelation of 3'-exonuclease activity in endonuclease V.
Biochemistry 44(34) , 11486-95, (2005) Endonuclease V is an enzyme that initiates a conserved DNA repair pathway by making an endonucleolytic incision at the 3' side one nucleotide from a deaminated base lesion. Site-directed mutagenesis analysis was conducted at seven conserved motifs of the ther... |
|
|
The phosphodiesterase 3 inhibitor cilostamide enhances inotropic responses to glucagon but not to dobutamine in rat ventricular myocardium.
Eur. J. Pharmacol. 512(2-3) , 207-13, (2005) The effects of phosphodiesterase (PDE) inhibitors (1-3) on tissue cAMP concentrations and the inotropic responses to dobutamine and glucagon were investigated in electrically driven right ventricular strips of the rat heart. Dobutamine (0.3-100 microM) produc... |
|
|
Identification of RNA linkage isomers by anion exchange purification with electrospray ionization mass spectrometry of automatically desalted phosphodiesterase-II digests.
Anal. Biochem. 399(1) , 110-7, (2010) Among the possible contaminants unique to RNA are linkage isomers that are difficult to identify by standard oligonucleotide analysis techniques. In a prior study, we used nonporous and monolithic polymer anion exchangers for purification and demonstrated a m... |
|
|
Nitric oxide inhibits arginine-vasotocin-induced increase of water osmotic permeability in frog urinary bladder.
Pflugers Arch. 448(2) , 197-203, (2004) The present study addressed the question of whether nitric oxide (NO) participates in regulation of osmotic water permeability in the urinary bladder of the frog Rana temporaria L. Experiments were carried out on isolated, paired hemi-bladders filled with amp... |