盐酸莫西沙星
盐酸莫西沙星结构式
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常用名 | 盐酸莫西沙星 | 英文名 | Moxifloxacin HCl |
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| CAS号 | 186826-86-8 | 分子量 | 437.892 | |
| 密度 | N/A | 沸点 | 636.4ºC at 760 mmHg | |
| 分子式 | C21H25ClFN3O4 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 338.7ºC |
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Simple and accurate quantitative analysis of 20 anti-tuberculosis drugs in human plasma using liquid chromatography-electrospray ionization-tandem mass spectrometry.
J. Pharm. Biomed. Anal. 102 , 9-16, (2014) A simple and accurate liquid chromatography (LC)-tandem mass spectrometry (MS/MS) method for the quantitation of 20 anti-tuberculosis (anti-TB) drugs in human plasma, was developed as a tool for therapeutic drug monitoring. Two protein precipitation methods w... |
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Exogenous dopamine induces dehydroepiandrosterone sulfotransferase (rSULT2A1) in rat liver and changes the pharmacokinetic profile of moxifloxacin in rats.
Drug Metab. Pharmacokinet. 30(1) , 97-104, (2015) Dehydroepiandrosterone sulfotransferase (SULT2A1) plays an important role in the detoxification of hydroxyl-containing xenobitotics and in the regulation of the biological activities of hydroxysteroids. Although dopamine (DA) is a vital neurotransmitter, DA a... |
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Effect of norfloxacin and moxifloxacin on melanin synthesis and antioxidant enzymes activity in normal human melanocytes.
Mol. Cell Biochem. 401(1-2) , 107-14, (2015) Fluoroquinolone antibiotics provide broad-spectrum coverage for a number of infectious diseases, including respiratory as well as urinary tract infections. One of the important adverse effects of these drugs is phototoxicity which introduces a serious limitat... |
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Comparative analysis of two femtosecond LASIK platforms using iTRAQ quantitative proteomics.
Invest. Ophthalmol. Vis. Sci. 55(6) , 3396-402, (2014) New femtosecond laser platforms may reduce ocular surface interference and LASIK-associated dry eye. This study investigated tear protein profiles in subjects who underwent LASIK using two femtosecond lasers to assess differences in protein expression.This wa... |
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Separation and determination of quinolone antibacterials by capillary electrophoresis.
J. Chromatogr. Sci. 52(8) , 919-25, (2014) The migration behavior and separation of 13 quinolone antibacterials were investigated by capillary electrophoresis (CE). In order to predict the electrophoretic mobility, the protonation macroconstants of all the compounds were determined by pH-potentiometri... |
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Biopharmaceutical characterization of nebulized antimicrobial agents in rats: 1. Ciprofloxacin, moxifloxacin, and grepafloxacin.
Antimicrob. Agents Chemother. 58(7) , 3942-9, (2014) The aim of this study was to evaluate the biopharmaceutical characteristics of three fluoroquinolones (FQs), ciprofloxacin (CIP), moxifloxacin (MXF), and grepafloxacin (GRX), after delivery via a nebulized aerosol to rats. Bronchoalveolar lavages (BAL) were c... |
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Evaluation of the effect of scleral buckling on the anterior chamber angle using ASOCT.
J. Glaucoma 24(4) , 267-71, (2015) To evaluate the change in anterior chamber angle parameters after scleral buckling surgery using anterior segment optical coherence tomography (ASOCT).Fifty-five phakic eyes of 55 subjects undergoing scleral buckling with the placement of an encircling band f... |
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Wavefront-guided versus wavefront-optimized laser in situ keratomileusis for patients with myopia: a prospective randomized contralateral eye study.
Am. J. Ophthalmol. 157(6) , 1170-1178.e1, (2014) To compare the clinical outcomes of wavefront-guided and wavefront-optimized laser in situ keratomileusis (LASIK).Prospective, randomized, fellow-eye-controlled study.The setting was a single academic institution. The study population included 110 eyes of 55 ... |
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Contralateral eye-to-eye comparison of wavefront-guided and wavefront-optimized photorefractive keratectomy: a randomized clinical trial.
JAMA Ophthalmol. 133(1) , 51-9, (2015) Wavefront-guided (WFG) and wavefront-optimized (WFO) platforms for refractive surgery are designed for improved visual outcomes. It is unclear which treatment profile is superior for patients undergoing photorefractive keratectomy (PRK).To compare the safety,... |
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Profile of microbial keratitis after corneal collagen cross-linking.
Biomed Res. Int. 2014 , 340509, (2014) To report the profile of microbial keratitis occurring after corneal collagen cross-linking (CXL) in keratoconus patients.A retrospective analysis of 2350 patients (1715 conventional CXL, 310 transepithelial CXL, and 325 accelerated CXL) over 7 years (from Ja... |