顺-11,14-二十碳二烯酸
顺-11,14-二十碳二烯酸结构式
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常用名 | 顺-11,14-二十碳二烯酸 | 英文名 | eicosa-11,14-dienoic acid |
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| CAS号 | 2091-39-6 | 分子量 | 308.499 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 462.1±0.0 °C at 760 mmHg | |
| 分子式 | C20H36O2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 326.3±15.2 °C |
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GC-EI-MS analysis of fatty acid composition in brain and serum of twitcher mouse.
Lipids 49(11) , 1115-25, (2014) Globoid cell leukodystrophy or Krabbe disease is an inherited autosomal recessive disorder caused by mutations in the galactosylceramidase gene. The objective of the study was to present information about the fatty acid (FA) composition of the brain and serum... |
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Serum fatty acid profiles and potential biomarkers of ankylosing spondylitis determined by gas chromatography-mass spectrometry and multivariate statistical analysis.
Biomed. Chromatogr. 29(4) , 604-11, (2015) Ankylosing spondylitis (AS) is a common chronic inflammatory rheumatic disease. Early and accurate detection is essential for effective disease treatment. Recently, research has focused on genomics and proteomics. However, the associated metabolic variations,... |
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Hypolipidemic activity in Sprague-Dawley rats and constituents of a novel natural vegetable oil from Cornus wilsoniana fruits.
J. Food Sci. 77(8) , H160-9, (2012) Cornus wilsoniana Wanger is a woody oil plant distributed in the south region of the Yellow River, China. Its oil has been taken as edible oil for over 100 y, and consumption of such oil is believed to prevent hyperlipidemia in Chinese folk recipe. This study... |
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Dietary linoleic acid has no effect on arachidonic acid, but increases n-6 eicosadienoic acid, and lowers dihomo-gamma-linolenic and eicosapentaenoic acid in plasma of adult men.
Prostaglandins Leukot. Essent. Fatty Acids 80(4) , 201-6, (2009) High intakes of linoleic acid (LA,18:2n-6) have raised concern due to possible increase in arachidonic acid (ARA, 20:4n-6) synthesis, and inhibition of alpha linolenic acid (ALA, 18:3n-3) desaturation to eicosapentaenoic (EPA, 20:5n-3) and docosahexaenoic aci... |
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An alternate pathway to long-chain polyunsaturates: the FADS2 gene product Delta8-desaturates 20:2n-6 and 20:3n-3.
J. Lipid Res. 50(6) , 1195-202, (2009) The mammalian Delta6-desaturase coded by fatty acid desaturase 2 (FADS2; HSA11q12-q13.1) catalyzes the first and rate-limiting step for the biosynthesis of long-chain polyunsaturated fatty acids. FADS2 is known to act on at least five substrates, and we hypot... |
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Reaction of prostaglandin endoperoxide synthase with cis,cis-eicosa-11,14-dienoic acid.
J. Biol. Chem. 273(11) , 6046-9, (1998) The pre-steady-state phase of the oxygenase reaction of prostaglandin endoperoxide synthase with cis,cis-eicosa-11, 14-dienoic acid has been studied using stopped flow techniques. Because some intermediate forms of prostaglandin endoperoxide synthase are spec... |
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Activation of the neutrophil NADPH-oxidase by free fatty acids requires the ionized carboxyl group and partitioning into membrane lipid.
J. Leukoc. Biol. 49(4) , 360-8, (1991) To investigate NADPH-oxidase activation, we studied the effects of free fatty acid (FFA), their uncharged derivatives, and calcium on membrane lipid structure and superoxide anion (O2-) release from intact neutrophils and in cell-free O2(-)-generating systems... |
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Effect of Trolox C on the oxygenation reaction of prostaglandin endoperoxide synthase with cis,cis-eicosa-11, 14-dienoic acid.
Prostaglandins Leukot. Essent. Fatty Acids 54(5) , 341-9, (1996) Trolox C, a water-soluble derivative of alpha-tocopherol, stimulates the oxygenation of cis,cis-eicosa-11, 14-dienoic acid (AH) by prostaglandin endoperoxide synthase at lower concentrations and suppresses the stimulated reaction at higher concentrations. Sur... |
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Oxygenation reactions of prostaglandins endoperoxide synthase and soybean lipoxygenase. Surprising stoichiometry in the formation of hydroperoxy and hydroxy derivatives of cis,cis-eicosa-11,14-dienoic acid.
Prostaglandins Leukot. Essent. Fatty Acids 53(6) , 423-31, (1995) The stoichiometry of the oxygenation reaction of cis,cis-eicosa-11,14-dienoic acid catalyzed by prostaglandin endoperoxide synthase and soybean lipoxygenase has been investigated by using steady-state initial rate measurements. The rate of product formation (... |
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Inhibition studies of soybean and human 15-lipoxygenases with long-chain alkenyl sulfate substrates.
Biochemistry 40(14) , 4391-7, (2001) Lipoxygenases are currently potential targets for therapies against asthma, artherosceloris, and cancer. Recently, inhibition studies on both soybean (SLO) and human lipoxygenase (15-HLO) revealed the presence of an allosteric site that binds both substrate, ... |