盐酸丙卡特罗
盐酸丙卡特罗结构式
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常用名 | 盐酸丙卡特罗 | 英文名 | Procaterol Hydrochloride |
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| CAS号 | 62929-91-3 | 分子量 | 326.818 | |
| 密度 | N/A | 沸点 | 539.5ºC at 760 mmHg | |
| 分子式 | C16H23ClN2O3 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 280.1ºC |
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Randomized, Multicenter Clinical Study of Tratinterol Hydrochloride Tablets for the Treatment of Bronchial Asthma.
Clin. Ther. 37 , 1248-58, (2015) The aim of this study was to determine the efficacy and safety profile of tratinterol hydrochloride tablets in the treatment of bronchial asthma.This multicenter, randomized, double-blind clinical research study was completed at 6 centers in the People's Repu... |
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Adenosine activation of A(2B) receptor(s) is essential for stimulated epithelial ciliary motility and clearance.
Am. J. Physiol. Lung Cell. Mol. Physiol. 301(2) , L171-80, (2011) Mucociliary clearance, vital to lung clearance, is dependent on cilia beat frequency (CBF), coordination of cilia, and the maintenance of periciliary fluid. Adenosine, the metabolic breakdown product of ATP, is an important modulator of ciliary motility. Howe... |
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Aerosol characteristics of admixture of budesonide inhalation suspension with a beta2-agonist, procaterol.
Allergol. Int. 62(1) , 131-5, (2013) Nebulized drugs for asthma treatment are often mixed together in order to simplify inhalation regimens, although not recommended. We therefore evaluated aerosol characteristics and physicochemical stability of the admixture of an inhaled corticosteroid suspen... |
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Binding pockets of the beta(1)- and beta(2)-adrenergic receptors for subtype-selective agonists.
Mol. Pharmacol. 56 , 875-885, (1999) We examined the subtype-selective binding site of the beta-adrenergic receptors (betaARs). The beta(1)/beta(2)-chimeric receptors showed the importance of the second and seventh transmembrane domains (TM2 and TM7) of the beta(2)AR for the binding of the beta(... |
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Metabolic response to various beta-adrenoceptor agonists in beta3-adrenoceptor knockout mice: evidence for a new beta-adrenergic receptor in brown adipose tissue.
Br. J. Pharmacol. 124 , 1684, (1998) The beta3-adrenoceptor plays an important role in the adrenergic response of brown and white adipose tissues (BAT and WAT). In this study, in vitro metabolic responses to beta-adrenoceptor stimulation were compared in adipose tissues of beta3-adrenoceptor kno... |
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Species differences in the distribution of beta-adrenoceptor subtypes in bladder smooth muscle.
Br. J. Pharmacol. 124 , 593-599, (1998) 1. The beta-adrenoceptor (beta-AR) subtypes mediating relaxation of the rabbit, rat and canine detrusors were subjected to functional investigation using selective beta-AR agonists and antagonists. 2. In all three species, isoprenaline, noradrenaline and adre... |
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UGT1A1*28 is associated with greater decrease in serum K⁺ levels following oral intake of procaterol.
J. Asthma 52 , 240-5, (2015) Procaterol is a potent β2-agonist frequently used for the management of asthma and chronic obstructive pulmonary disease. The efficacy and adverse effects of β2-agonists are heterogeneous in individual patients, which may be partly caused by genetic variation... |
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Structure and function of an irreversible agonist-β(2) adrenoceptor complex.
Nature 469(7329) , 236-40, (2011) G-protein-coupled receptors (GPCRs) are eukaryotic integral membrane proteins that modulate biological function by initiating cellular signalling in response to chemically diverse agonists. Despite recent progress in the structural biology of GPCRs, the molec... |
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The effect of β-2 adrenoreceptor agonist inhalation on lungs donated after cardiac death in a canine lung transplantation model.
J. Heart Lung Transplant. 31(7) , 773-9, (2012) It is a matter of great importance in a donation after cardiac death to attenuate ischemia-reperfusion injury (IRI) related to the inevitable warm ischemic time.Donor dogs were rendered cardiac-dead and left at room temperature. The dogs were allocated into 2... |
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Procaterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells.
Eur. J. Pharmacol. 650(1) , 431-44, (2011) β(2) agonists reduce the frequency of exacerbations in patients with bronchial asthma and chronic obstructive pulmonary disease caused by respiratory virus infection. β(2) agonists reduce the production of pro-inflammatory cytokines. However, the inhibitory e... |