曲克芦丁
曲克芦丁结构式
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常用名 | 曲克芦丁 | 英文名 | Troxerutin |
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| CAS号 | 7085-55-4 | 分子量 | 742.675 | |
| 密度 | 1.7±0.1 g/cm3 | 沸点 | 1058.4±65.0 °C at 760 mmHg | |
| 分子式 | C33H42O19 | 熔点 | 168 - 176ºC | |
| MSDS | 中文版 美版 | 闪点 | 332.0±27.8 °C |
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Analysis of changes in microRNA expression profiles in response to the troxerutin-mediated antioxidant effect in human dermal papilla cells.
Mol. Med. Report. 12 , 2650-60, (2015) Dermal papilla (DP) cells function as important regulators of the hair growth cycle. The loss of these cells is a primary cause of diseases characterized by hair loss, including alopecia, and evidence has revealed significantly increased levels of reactive ox... |
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Phlebotonics for haemorrhoids.
Cochrane Database Syst. Rev. 8 , CD004322, (2012) Haemorrhoids are variceal dilatations of the anal and perianal venous plexus and often develop secondary to the persistently elevated venous pressure within the haemorrhoidal plexus (Kumar 2005). Phlebotonics are a heterogenous class of drugs consisting of pl... |
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Troxerutin, a plant flavonoid, protects cells against oxidative stress-induced cell death through radical scavenging mechanism.
Food Chem. 194 , 32-45, (2015) Troxerutin (TRX) is a flavonoid present in tea, coffee, cereal grains, various fruits and vegetables have been reported to exhibit radioprotective, antithrombotic, nephro and hepato-protective effects. A systematic study was undertaken to evaluate its free ra... |
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Effect of troxerutin on insulin signaling molecules in the gastrocnemius muscle of high fat and sucrose-induced type-2 diabetic adult male rat.
Mol. Cell Biochem. 395(1-2) , 11-27, (2014) Troxerutin is a trihydroxyethylated derivative of the flavonoid, rutin. It has been reported to possess the hepatoprotective, nephroprotective, antioxidant, anti-inflammatory, and antihyperlipidemic activities. Troxerutin treatment reduced the blood glucose a... |
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Pharmacological treatment in patients with C4, C5 and C6 venous disease.
Phlebology 25 Suppl 1 , 35-41, (2010) A range of surgical, endovenous, physical and medical treatments are available for patients with chronic venous disease. The aim of this review was to evaluate the evidence for pharmacological agents used for the treatment of chronic venous disease.A literatu... |
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Calcium dobesilate and oxerutin: effectiveness of combination therapy.
Phlebology 25(2) , 66-71, (2010) Chronic venous insufficiency (CVI) is an important cause of discomfort and inability to work. Hydroxyethylrutosides (Venoruton); 0-[beta-hydroxyethyl]-rutosides) has been used for decades for the treatment of CVI. Studies have reported symptomatic relief and ... |
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Pharmacological agents in the treatment of venous disease: an update of the available evidence.
Curr. Vasc. Pharmacol. 7(3) , 303-8, (2009) Varicose veins and the complications of venous disease are thought to affect over a quarter of the adult population and the management of these conditions are a major cause of health service expense. Advances in the understanding of venous pathophysiology hav... |
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Treatment of the common cold with troxerutin.
APMIS 112(9) , 605-11, (2004) The rutosides are naturally occurring flavonoids that have documented effects on capillary permeability and edema. The purpose of this study was to assess the effect of troxerutin, one of the rutosides, on the symptoms of the common cold. Ninety-four voluntee... |
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Comparison of the effects of troxerutin and heparinoid on flap necrosis
J. Plast. Reconstr. Aesthet. Surg. 63(5) , 875-83, (2010) We aimed to assess the effects of local troxerutin and heparinoid (HEP) treatments in a model of flap necrosis. Three groups of Wistar albino rats, each comprising 10 animals were used. A cranially based 6 × 3-cm full-thickness random-pattern skin flap was ra... |
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Radioprotective effects of troxerutin against gamma irradiation in mice liver.
Int. J. Radiat. Biol. 88(8) , 607-12, (2012) The purpose of this study was to conduct research in mice to determine the radioprotective effects of troxerutin. Thirty-day survival, oxidative status and histological changes in the liver were all evaluated.Troxerutin was administered orally to mice for six... |