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丁卡因碱

丁卡因碱结构式
丁卡因碱结构式
品牌特惠专场
常用名 丁卡因碱 英文名 UNII:TF4710DNP9
CAS号 5094-24-6 分子量 126.086
密度 1.195g/cm3 沸点 238.3ºC at 760mmHg
分子式 C4H7NaO3 熔点 133-135 °C(lit.)
MSDS 中文版 美版 闪点 112.2ºC

Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice.

PLoS Pathog. 11(2) , e1004645, (2015)

The identification of Mycobacterium tuberculosis genes necessary for persistence in vivo provides insight into bacterial biology as well as host defense strategies. We show that disruption of M. tuberculosis membrane protein PerM (Rv0955) resulted in an IFN-γ...

Ultrastructural morphologic changes in mycobacterial biofilm in different extreme condition.

Ultrastruct. Pathol. 39(1) , 38-48, (2015)

The aim of this study was to investigate the morphologic and ultrastructural features of biofilms of slow and fast-growing mycobacteria in different stress conditions, presence and absence of oleic acid albumin dextrose catalase (OADC) enrichment and at diffe...

Accurate analysis of ginkgolides and their hydrolyzed metabolites by analytical supercritical fluid chromatography hybrid tandem mass spectrometry.

J. Chromatogr. A. 1388 , 251-8, (2015)

Hydrolysis plays an important role in the metabolic transformations of lactones. Analysis of lactones and their hydrolyzed metabolites in biological samples is challenging, because unexpected hydrolysis or reversed dehydration may occur depending on the test ...

Liposome encapsulated soy lecithin and cholesterol can efficiently replace chicken egg yolk in human semen cryopreservation medium.

Syst. Biol. Reprod. Med. 60(3) , 183-8, (2014)

Cryopreservation of spermatozoa plays a significant role in reproductive medicine and fertility preservation. Chicken egg yolk is used as an extender in cryopreservation of human spermatozoa using glycerol egg yolk citrate (GEYC) buffered medium. Even though ...

Factors affecting formulation characteristics and stability of ascorbic acid in water-in-oil creams.

Int. J. Cosmet. Sci. 36(5) , 494-504, (2014)

The present investigation is based on the formulation of water-in-oil (w/o) cream preparations of ascorbic acid (AA) at pH 4-6 using different emollients and humectants.The preparations were stored in the dark at 30°C for a period of 3 months and were studied...

Affinity precipitation of a monoclonal antibody from an industrial harvest feedstock using an ELP-Z stimuli responsive biopolymer.

Biotechnol. Bioeng. 111(8) , 1595-603, (2014)

In this work, a proof of concept elastin-like polypeptide-Z domain fusion (ELP-Z) based affinity precipitation process is developed for monoclonal antibody (mAb) purification from industrial harvest feeds. Greater than 99% mAb recoveries are obtained during t...

Ultrasonication as a potential tool to predict solute crystallization in freeze-concentrates.

Pharm. Res. 31(6) , 1512-24, (2014)

We hypothesize that ultrasonication can accelerate solute crystallization in freeze-concentrates. Our objective is to demonstrate ultrasonication as a potential predictive tool for evaluating physical stability of excipients in frozen solutions.The crystalliz...

Comparative experimental subcutaneous glanders and melioidosis in the common marmoset (Callithrix jacchus).

Int. J. Exp. Pathol. 95(6) , 378-91, (2014)

Glanders and melioidosis are caused by two distinct Burkholderia species and have generally been considered to have similar disease progression. While both of these pathogens are HHS/CDC Tier 1 agents, natural infection with both these pathogens is primarily ...

Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream.

Eur. J. Pharm. Biopharm. 88(3) , 614-24, (2015)

A novel adapalene-loaded solid lipid microparticle (SLMA) dispersion as a topical drug delivery system (TDDS) for follicular penetration has been introduced. The objective of the present study was to investigate the rheological properties, the follicular pene...

Enhancing perception of contaminated food through acid-mediated modulation of taste neuron responses.

Curr. Biol. 24(17) , 1969-77, (2014)

Natural foods contain not only nutrients, but also nonnutritious and potentially harmful chemicals. Thus, animals need to evaluate food content in order to make adequate feeding decisions.Here, we investigate the effects of acids on the taste neuron responses...