β-烟酰胺腺嘌呤二核苷酸磷酸钠盐
β-烟酰胺腺嘌呤二核苷酸磷酸钠盐结构式
|
常用名 | β-烟酰胺腺嘌呤二核苷酸磷酸钠盐 | 英文名 | β-NADP-sodium salt |
|---|---|---|---|---|
| CAS号 | 1184-16-3 | 分子量 | 765.387 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C21H27N7NaO17P3 | 熔点 | 175-178ºC | |
| MSDS | 美版 | 闪点 | N/A |
|
Alanine Scanning Mutagenesis Identifies an Asparagine–Arginine–Lysine Triad Essential to Assembly of the Shell of the Pdu Microcompartment
J. Mol. Biol. 426(12) , 2328-45, (2014) Bacterial microcompartments (MCPs) are the simplest organelles known. They function to enhance metabolic pathways by confining several related enzymes inside an all-protein envelope called the shell. In this study, we investigated the factors that govern MCP ... |
|
|
Increasing mitochondrial muscle fatty acid oxidation induces skeletal muscle remodeling toward an oxidative phenotype.
FASEB J. 29 , 2473-83, (2015) Adult skeletal muscle is a dynamic, remarkably plastic tissue, which allows myofibers to switch from fast/glycolytic to slow/oxidative types and to increase mitochondrial fatty acid oxidation (mFAO) capacity and vascularization in response to exercise trainin... |
|
|
Chenodeoxycholic acid, an endogenous FXR ligand alters adipokines and reverses insulin resistance.
Mol. Cell. Endocrinol. 414 , 19-28, (2015) Adipose tissue secretes adipokines that regulate insulin sensitivity in adipocytes and other peripheral tissues critical to glucose metabolism. Insulin resistance is associated with severe alterations in adipokines characterized by release of increased pro-in... |
|
|
The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene.
Toxicol. Sci. 147 , 339-49, (2015) Exposure to the ubiquitous environmental contaminant trichloroethylene (TCE) is associated with cancer and non-cancer toxicity in both humans and rodents. Peroxisome proliferator-activated receptor-alpha (PPARα) is thought to be playing a role in liver toxici... |
|
|
C-phycocyanin prevents cisplatin-induced mitochondrial dysfunction and oxidative stress.
Mol. Cell Biochem. 406 , 183-97, (2015) The potential of C-phycocyanin (C-PC) to prevent cisplatin (CP)-induced kidney mitochondrial dysfunction was determined in CD-1 male mice. The CP-induced mitochondrial dysfunction was characterized by ultrastructural abnormalities and by decrease in the follo... |
|
|
Point-of-Care Quantitative Measure of Glucose-6-Phosphate Dehydrogenase Enzyme Deficiency.
Pediatrics 136 , e1268-75, (2015) Widespread newborn screening on a point-of-care basis could prevent bilirubin neurotoxicity in newborns with glucose-6-phosphate dehydrogenase (G6PD) deficiency. We evaluated a quantitative G6PD assay on a digital microfluidic platform by comparing its perfor... |
|
|
A comparison of in vitro ADME properties and pharmacokinetics of azithromycin and selected 15-membered ring macrolides in rodents.
Eur. J. Drug Metab. Pharmacokinet. 39(4) , 263-76, (2014) The purpose of this study was to evaluate the impact of structural modifications on the 15-membered macrolactone ring and/or substituents on the in vitro ADME properties and in vivo pharmacokinetic (PK) profile for selected derivatives in rodents in compariso... |
|
|
The effect of cloudy apple juice on hepatic and mammary gland phase I and II enzymes induced by DMBA in female Sprague-Dawley rats.
Drug Chem. Toxicol. 37(4) , 472-9, (2014) Apples abundant in phenolic compounds show a variety of biological activities that may contribute to health beneficial effects against cardiovascular diseases, diabetes, obesity and cancer. We investigated the effect of cloudy apple juice (CAJ) on the hepatic... |
|
|
Paroxetine decreased plasma exposure of glyburide partly via inhibiting intestinal absorption in rats.
Drug Metab. Pharmacokinet. 30 , 240-6, (2015) Accumulating evidences have shown that diabetes is often accompanied with depression, thus it is possible that oral antidiabetic agent glyburide and antidepressive agent paroxetine are co-administered in diabetic patients. The aim of this study was to assess ... |
|
|
In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach.
Toxicol. Appl. Pharmacol. 281(3) , 276-84, (2014) 1,3-Butadiene (BD) is a rodent and human carcinogen. In the cancer tests, mice have been much more susceptible than rats with regard to BD-induced carcinogenicity. The species-differences are dependent on metabolic formation/disappearance of the genotoxic BD ... |