2-溴-5-氟苯甲醛
2-溴-5-氟苯甲醛结构式
|
常用名 | 2-溴-5-氟苯甲醛 | 英文名 | 2-Bromo-5-fluorobenzaldehyde |
|---|---|---|---|---|
| CAS号 | 94569-84-3 | 分子量 | 203.008 | |
| 密度 | 1.7±0.1 g/cm3 | 沸点 | 225.8±20.0 °C at 760 mmHg | |
| 分子式 | C7H4BrFO | 熔点 | 51-56 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 90.4±21.8 °C |
|
5-Fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol.
Acta Crystallogr. Sect. E Struct. Rep. Online 67(Pt 2) , o414-5, (2011) In the crystal structure of the title compound, C(7)H(6)BFO(2), a broad-spectrum anti-fungal drug (AN2690), the planar [maximum deviation 0.035 (1) Å] mol-ecules form centrosymmetric R(2) (2)(8) dimers via strong O-H⋯O hydrogen bonds. The dimers are arranged ... |
|
|
Discovery of a new boron-containing antifungal agent, 5-fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the potential treatment of onychomycosis.
J. Med. Chem. 49(15) , 4447-50, (2006) A structure-activity relationship investigation for a more efficacious therapy to treat onychomycosis, a fungal infection of the toe and fingernails, led to the discovery of a boron-containing small molecule, 5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (... |
|
|
2-Bromo-5-fluorobenzaldehyde. Tureski RE and Tanski JM.
Acta Crystallogr. Sect. E Struct. Rep. Online 69(8) , o1246-o1246, (2013)
|
|
|
Nuclear spin-spin coupling via nonbonded interactions. 4. Fluorine-fluorine and hydrogen-fluorine coupling in substituted benzo [c] phenanthrenes. Mallory FB, et al.
J. Org. Chem. 50(4) , 457-461, (1985)
|