DL-2-氨基丙酸
DL-2-氨基丙酸结构式
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常用名 | DL-2-氨基丙酸 | 英文名 | DL-Alanine |
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| CAS号 | 302-72-7 | 分子量 | 89.093 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 212.9±23.0 °C at 760 mmHg | |
| 分子式 | C3H7NO2 | 熔点 | 272-275ºC | |
| MSDS | 中文版 美版 | 闪点 | 82.6±22.6 °C |
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Hepatitis E virus (HEV) protease: a chymotrypsin-like enzyme that processes both non-structural (pORF1) and capsid (pORF2) protein.
J. Gen. Virol. 95(Pt 8) , 1689-700, (2014) Hepatitis E virus (HEV), a major cause of acute viral hepatitis across the world, is a non-enveloped, plus-strand RNA virus. Its genome codes three proteins, pORF1 (multifunctional polyprotein), pORF2 (capsid protein) and pORF3 (multi-regulatory protein). pOR... |
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Rad23 interaction with the proteasome is regulated by phosphorylation of its ubiquitin-like (UbL) domain.
J. Mol. Biol. 426(24) , 4049-60, (2014) Rad23 was identified as a DNA repair protein, although a role in protein degradation has been described. The protein degradation function of Rad23 contributes to cell cycle progression, stress response, endoplasmic reticulum proteolysis, and DNA repair. Rad23... |
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Identification of protein tyrosine phosphatase receptor gamma extracellular domain (sPTPRG) as a natural soluble protein in plasma.
PLoS ONE 10(3) , e0119110, (2015) PTPRG is a widely expressed protein tyrosine phosphatase present in various isoforms. Peptides from its extracellular domain have been detected in plasma by proteomic techniques. We aim at characterizing the plasmatic PTPRG (sPTPRG) form and to identify its s... |
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Inhaled lactonase reduces Pseudomonas aeruginosa quorum sensing and mortality in rat pneumonia.
PLoS ONE 9(10) , e107125, (2014) The effectiveness of antibiotic molecules in treating Pseudomonas aeruginosa pneumonia is reduced as a result of the dissemination of bacterial resistance. The existence of bacterial communication systems, such as quorum sensing, has provided new opportunitie... |
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Direct silylation of Trypanosoma brucei metabolites in aqueous samples and their GC-MS/MS analysis.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 967 , 134-8, (2014) A simple two-step method for the derivatization of polar compounds (lactate, alanine, glycerol, succinate and glucose) using hexamethyldisilazane (HMDS) and N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA) was developed. This method allows direct derivatizat... |
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In vitro and in vivo replication of a chemically synthesized consensus genome of hepatitis B virus genotype B.
J. Virol. Methods 213 , 57-64, (2015) Hepatitis B virus (HBV) genotypes vary in their geographical distribution and virological features. Previous investigations have shown that HBV genotype B is a predominant HBV genotype in China. Studies on HBV concerning different isolates frequently meet the... |
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Investigation of a Degradant in a Biologics Formulation Buffer Containing L-Histidine.
Pharm. Res. 32 , 2625-35, (2015) An unknown UV 280 nm absorbing peak was observed by SEC for protein stability samples formulated in L-histidine during a stress stability study. Understanding the source would enhance the confidence in the SEC results. We identified the unknown peak, studied ... |
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Preclinical evaluation of a Haemophilus influenzae type b conjugate vaccine process intended for technology transfer.
Hum. Vaccin. Immunother. 10(9) , 2691-6, (2014) Introduction of Haemophilus influenzae type b (Hib) vaccine in low- and middle-income countries has been limited by cost and availability of Hib conjugate vaccines for a long time. It was previously recognized by the Institute for Translational Vaccinology (I... |
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An attenuated phenotype of Costello syndrome in three unrelated individuals with a HRAS c.179G>A (p.Gly60Asp) mutation correlates with uncommon functional consequences.
Am. J. Med. Genet. A 167A , 2085-97, (2015) Heterozygous germline mutations in the proto-oncogene HRAS cause Costello syndrome (CS), an intellectual disability condition with severe failure to thrive, cardiac abnormalities, predisposition to tumors, and neurologic abnormalities. More than 80% of patien... |
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Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol.
Int. J. Mol. Sci. 16 , 22062-80, (2015) In this study, the effects of mixed corn peptides and synthetic pentapeptide (QLLPF) on hepatocyte apoptosis induced by ethanol were investigated in vivo. QLLPF, was previously characterized from corn protein hydrolysis, which had been shown to exert good fac... |