One-pot synthesis of various 2, 3-polymethylene-4 (3H)-quinazolinones from anthranilic acid, corresponding lactam and SOCl 2 is described, which can be applicable to the synthesis of simple 4 (3H)-quinazolinone-derived alkaloids, such as luotonin A, tryptanthrin, and rutaecarpine.
![3-chloro-6,7,8,9-tetrahydropyrido[2,1-b]quinazolin-11-one结构式](https://image.chemsrc.com/caspic/195/60811-46-3.png)
![7-氯-1h,2h,3h,9h-吡咯并[2,1-b]喹唑啉-9-酮结构式](https://image.chemsrc.com/caspic/288/60811-39-4.png)
![2-chloro-6,7,8,9-tetrahydropyrido[2,1-b]quinazolin-11-one结构式](https://image.chemsrc.com/caspic/157/60811-47-4.png)
![7-iodo-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one结构式](https://image.chemsrc.com/caspic/072/61938-66-7.png)
![7-hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one结构式](https://image.chemsrc.com/caspic/340/85654-22-4.png)
![6,7,8,9,10,11-hexahydroazocino[2,1-b]quinazolin-13-one结构式](https://image.chemsrc.com/caspic/472/58314-97-9.png)