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Microwave??Assisted Deacylation of Unactivated Amides Using Ammonium??Salt??Accelerated Transamidation

…, H Morimoto, M Zhang, T Ohshima

文献索引:Shimizu, Yuhei; Morimoto, Hiroyuki; Zhang, Ming; Ohshima, Takashi Angewandte Chemie - International Edition, 2012 , vol. 51, # 34 p. 8564 - 8567

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被引用次数: 31

摘要

Amines are ubiquitous organic molecules in natural products and pharmaceuticals [1] and efficient synthesis of amines is an important topic in synthetic organic chemistry. Recent efforts to streamline organic synthesis favors the use of unprotected molecules in synthetic protocols,[2] but amine protection is still a reliable way to obtain satisfactory yields of the desired products and unprotected amines are often too reactive to avoid undesired ...

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