阿洛西林钠

更新时间：2025-08-20 20:55:19

阿洛西林钠结构式	常用名	阿洛西林钠	英文名	Azlocillin sodium salt
	CAS号	37091-65-9	分子量	483.473
	密度	N/A	沸点	N/A
	分子式	C₂₀H₂₂N₅NaO₆S	熔点	N/A
	MSDS	中文版美版	闪点	N/A
	符号	GHS08	信号词	Danger

阿洛西林钠用途

【用途一】
为半合成广谱抗霉素，对绿脓杆菌、厌氧杆菌、大肠杆菌等有抗菌活性

【用途二】
为抗生素类药

中文名	阿洛西林钠
英文名	azlocillin sodium
中文别名	(2S,5R,6R)-3,3-二甲基-6-[[[[(2-氧代-1-咪唑烷基)羰基]氨基]苯基乙酰基]氨基]-7-氧代-4-硫杂-1-氮杂双环[3,2,0]庚烷-2-羧酸钠盐 \| 环吡司胺
英文别名	更多

描述	Azlocillin是广谱抗菌素。
相关类别	信号通路 >> 抗感染 >> 细菌研究领域 >> 感染
参考文献	[1]. Stewart, D. and G.P. Bodey, Azlocillin: in vitro studies of a new semisynthetic penicillin. Antimicrob Agents Chemother, 1977. 11(5): p. 865-70. [2]. Wright, A.J., The penicillins. Mayo Clin Proc, 1999. 74(3): p. 290-307. [3]. McFarland, M.M., E.M. Scott, and A. Li Wan Po, Time-survival studies for quantifying effects of azlocillin and tobramycin on Pseudomonas aeruginosa. Antimicrob Agents Chemother, 1994. 38(6): p. 1271-6. [4]. Livermore, D.M. and H.Y. Chen, Quality of antimicrobial susceptibility testing in the UK: a Pseudomonas aeruginosa survey revisited. J Antimicrob Chemother, 1999. 43(4): p. 517-22.

描述

Azlocillin是广谱抗菌素。

相关类别

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

参考文献

[1]. Stewart, D. and G.P. Bodey, Azlocillin: in vitro studies of a new semisynthetic penicillin. Antimicrob Agents Chemother, 1977. 11(5): p. 865-70.

[2]. Wright, A.J., The penicillins. Mayo Clin Proc, 1999. 74(3): p. 290-307.

[3]. McFarland, M.M., E.M. Scott, and A. Li Wan Po, Time-survival studies for quantifying effects of azlocillin and tobramycin on Pseudomonas aeruginosa. Antimicrob Agents Chemother, 1994. 38(6): p. 1271-6.

[4]. Livermore, D.M. and H.Y. Chen, Quality of antimicrobial susceptibility testing in the UK: a Pseudomonas aeruginosa survey revisited. J Antimicrob Chemother, 1999. 43(4): p. 517-22.

分子式	C₂₀H₂₂N₅NaO₆S
分子量	483.473
精确质量	483.118835
PSA	176.28000
InChIKey	FUHFQQPUHNRIQM-XFAPPKAWSA-N
SMILES	CC1(C)SC2C(NC(=O)C(NC(=O)N3CCNC3=O)c3ccccc3)C(=O)N2C1C(=O)O.[Na]
储存条件	2-8°C

阿洛西林钠毒性英文版

符号	GHS08
信号词	Danger
危害声明	H317-H334
警示性声明	P261-P280-P342 + P311
个人防护装备	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
危害码 (欧洲)	Xn:Harmful
风险声明 (欧洲)	R42/43
安全声明 (欧洲)	S36
危险品运输编码	NONH for all modes of transport
WGK德国	3
RTECS号	XH9250000
海关编码	2942000000

海关编码	2942000000

High-pressure liquid chromatographic quantitation of azlocillin.

Antimicrob. Agents Chemother. 24 , 750-753, (1983)

We describe a rapid, precise, and simple procedure for the quantitation of azlocillin in serum and in aqueous solutions by high-pressure, reverse-phase liquid chromatography. This method uses a single...

Structure-Activity Relationships of Different β-Lactam Antibiotics against a Soluble Form of Enterococcus faecium PBP5, a Type II Bacterial Transpeptidase. Andrea M. Hujer, Malgosia Kania, et. Al

J. Affect. Disord. 49 , 612-618, (2005)

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标：HCMV UL50
External Id：HMS1262

实验名称：ERK5 transcriptional activity HTS
来源：24565
靶标：N/A
External Id：ERK5 transcriptional activity-HTS

实验名称：Drug Induced Liver Injury Prediction System (DILIps) validation dataset; compound DIL...
来源：ChEMBL
靶标：Hepatotoxicity
External Id：CHEMBL1909323

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER...
来源：ChEMBL
靶标：Severe acute respiratory syndrome coronavirus 2
External Id：CHEMBL4513082

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac...
来源：ChEMBL
靶标：Severe acute respiratory syndrome coronavirus 2
External Id：CHEMBL4303805

实验名称：Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimo...
来源：ChEMBL
靶标：Solute carrier organic anion transporter family member 1B3
External Id：CHEMBL3039491

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f...
来源：ChEMBL
靶标：Replicase polyprotein 1ab
External Id：CHEMBL4495582

实验名称：Inhibition of cell viability relative to arbidol control (inhibition index > 1 indica...
来源：ChEMBL
靶标：Severe acute respiratory syndrome coronavirus 2
External Id：CHEMBL4303819

实验名称：Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimo...
来源：ChEMBL
靶标：Solute carrier organic anion transporter family member 1B1
External Id：CHEMBL3039488

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate
来源：ChEMBL
靶标：Histone deacetylase 6
External Id：CHEMBL4808149

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Azlocillin sodium

Sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-((R)-2-(2-oxo-1-imidazolidinecarboxamido)-2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-[[(2R)-2-[[(2-oxo-1-imidazolidinyl)carbonyl]amino]-2-phenylacetyl]amino]-, sodium salt, (2S,5R,6R)- (1:1)

MFCD07793330

Azlocillin sodium salt

Sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(2R)-2-{[(2-oxo-1-imidazolidinyl)carbonyl]amino}-2-phenylacetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

Azlin

Securopen

sodium azlocillin

monosodium azlocillin

EINECS 253-347-7

Azlocillin (sodium salt)