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多沙唑嗪

更新时间:2024-07-15 12:36:36 采购访问:17次

常用名 多沙唑嗪 CAS号 74191-85-8
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Doxazosin(UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.Target: Adrenergic ReceptorDoxazosin is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms [1]. doxazosin may have a direct inhibitory effect on cholesterol synthesis independent of the LDL receptor. The inhibition of cholesterol synthesis by doxazosin may cause cells to compensate by upregulating the LDL receptor, thereby increasing the importation of lipoprotein cholesterol and reducing LDL cholesterol in the medium [2]. Doxazosin monotherapy was effective in eight of 12 patients (66.7%), and combined therapy with a beta-blocker was effective in 11 of 12 patients (91.7%). The mean pulse rate remained constant throughout therapy. Adverse reactions were minor and transient and occurred in only three patients. Urinary and plasma catecholamine levels tended to decrease or remained unchanged during doxazosin therapy [3].Clinical indications: Hypertension; Prostate hyperplasiaFDA Approved Date: February 22, 2005Toxicity: Symptoms of overdose include hypotension
物理化学性质:
CAS号:74191-85-8
常用中文名:多沙唑嗪
常用英文名:Doxazosin
分子式:C23H25N5O5
分子量:451.48
密度:1.371 g/cm3
沸点:718ºC at 760 mmHg
熔点:289-290°C
闪点:388ºC
储存条件:-20℃

供应商信息

上海念兴实业有限公司 认证供应商

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商品数:403768件
电话:18916513247
地址:2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai
地区: 上海市 上海市 普陀区
联系人:小陈
联系人电话:0086-021-52280163
邮件:sales@echemcloud.com
网址:http://www.echemcloud.com
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参考价格:$70/100mg
其他供应商价格:
2022-03-04 多沙唑嗪
价格:¥230.9
2021-02-06 Doxazosin
价格:¥3293.0

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