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阿莫曲普坦

更新时间:2025-09-13 20:46:00 采购访问:27次

常用名 阿莫曲坦 CAS号 154323-57-6
价格 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Almotriptan is a 5-HT1B/1D-receptor agonist used to treat migraine.IC50:Target: 5-hydroxytryptamine1B/1D (5-HT1B/1D) ReceptorAlmotriptan is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults. Almotriptan showed low nanomolar affinity for the 5-HT(1B) and 5-HT(1D) receptors in several species, including the human, while affinity for 5-HT receptors other than 5-HT(1B/1D) was clearly less. Almotriptan did not exhibit significant affinity for several non-5-HT receptors studied up to 100 microM. Almotriptan inhibited forskolin-stimulated cyclic AMP accumulation in HeLa cells transfected with 5-HT(1B) or 5-HT(1D) human receptors [1]. Almotriptan had a mild antiemetic effect and a slight, transient diuretic effect in dogs, although the latter effect is probably of no clinical relevance. In addition, no effect on the respiratory system of conscious guinea pigs was observed following almotriptan treatment. These results indicate that almotriptan has a favourable safety profile with respect to the central nervous, renal and respiratory systems [2].
物理化学性质:
CAS号:154323-57-6
常用中文名:阿莫曲坦
常用英文名:Almotriptan
分子式:C17H25N3O2S
分子量:335.464
密度:1.3±0.1 g/cm3
沸点:538.7±60.0 °C at 760 mmHg
熔点:N/A
闪点:279.6±32.9 °C
储存条件:室温

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上海化源世纪贸易有限公司 认证供应商

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参考价格:$72/10mg
其他供应商价格:
2022-03-04 盐酸阿莫曲坦-d6
价格:¥1896.0

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