| 常用名 | GGTI-286 | CAS号 | 171744-11-9 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: GGTI-286, a potent and cell-permeable GGTase I inhibitor, is 25-fold more potent (IC50=2 μM) than the corresponding methyl ester of FTI-276 (HY-15873A). GGTI-286 selectively inhibits geranylgeranylation of Rap1A over farnesylation of H-Ras in NIH3T3 cells (IC50s =2 and >30 μM, respectively). GGTI-286 also potently inhibits oncogenic K-Ras4B stimulation with an IC50 of 1 μM[1]. 物理化学性质: CAS号:171744-11-9 常用中文名:GGTI-286 常用英文名:GGTI-286 分子式:C23H31N3O3S 分子量:429.58 密度:1.2±0.1 g/cm3 沸点:626.9±55.0 °C at 760 mmHg 熔点:N/A 闪点:332.9±31.5 °C 储存条件:-20°C,干燥,密封 |